In addition to Pattison, the district also serves the city of Brookshire and the community of Sunnyside.[2]
The district was established in January 1959 as the Pattison-Brookshire Consolidated Independent School District, when the citizens of the Brookshire and Pattison School Districts voted to consolidate. In February 1960, the Board of Trustees adopted the district's current name.
Cleveland ISD extends into portions of Montgomery and San Jacinto counties, and Tomball ISD extends into portions of Montgomery County. Other districts in those counties are served by Region 6 ESC.