The diocese was erected in 1559 by papal bull Super universas to become independent of the Diocese of Tournai. Ghent had an important local administration and was the location of the Abbey of Saint Bavo, founded by Saint Amandus. However, this abbey was suppressed and the canons were removed, moving to the collegiate church of Saint John, and it changed its name to Saint Bavo. This collegiate church became the see of the current diocese. The diocese was created from the surrounding dioceses in Belgium.
Territorial structure
Originally, the diocese was much larger and contained the city of Hulst. Currently, the diocese is coextensive with the Belgian province of East Flanders, in addition to the municipality of Zwijndrecht, which is in the secular Province of Antwerp.