Combe, having left Uruguay aged eleven, began his career in Argentina with Vélez Sarsfield.[2][3][4] He never made a senior appearance for the club, though was on the substitutes bench for Primera División fixtures with Atlético de Rafaela and Colón in August 2015; as well as in the Copa Argentina versus Acassuso.[2] On 22 July 2016, Combe was loaned to Primera B Metropolitana's Fénix.[2] His professional debut came in a loss to Platense on 4 September, on the way to seven total appearances for them; with his first goal coming in his last match, versus Colegiales in October.[2][5] Despite no further games, he remained with Fénix until June 2017.[6]
In August 2018, Combe switched Vélez Sarsfield for Deportivo Español; in a permanent deal.[2][7] Fourteen appearances followed across the 2018–19 campaign as they suffered relegation.[2][8][9][10]