Region 4 or Region IV can refer to:

• One of the DVD region codes
• Region 4, Northwest Territories (Canadian census)
• The West of the US (one of four regions of the US census)
• One of the health regions of Canada managed by Vitalité Health Network
• Former Region 4 (Johannesburg), an administrative district in the city of Johannesburg, South Africa, from 2000 to 2006
• One of the Regions of Iran
• Coquimbo Region, Chile
• Southern Tagalog, Philippines
• Calabarzon, Philippines

This disambiguation page lists articles associated with the title Region 4.
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