In Keyton's freshman season in 2019, he tallied four receptions for 104 yards, while also rushing for ten yards.[3] During the 2020 season, Keyton played in seven games notching nine receptions for 76 yards.[4] During the 2021 season, Keyton totaled seven receptions for 72 yards.[5] In week seven of the 2022 season, Keyton had 77 yards and two touchdowns in a win over UT Martin.[6] In the 2022 Orange Bowl, Keyton hauled in four receptions for 76 yards and a touchdown versus Clemson.[7] Keyton finished the 2022 season bringing in 31 receptions for 562 yards and five touchdowns.[8] During the 2023 season, Keyton would start all 13 games for the Volunteers, where he notched 35 receptions for 642 yards and six touchdowns.[9] After the conclusion of the 2023 season, Keyton decided to declare for the 2024 NFL draft.[10][11]
After not being selected in the 2024 NFL draft, Keyton decided to sign with the Las Vegas Raiders as an undrafted free agent.[13][14] After an impressive preseason, Keyton made the Raiders initial 53-man roster as an undrafted rookie. He was waived on September 28, and re-signed to the practice squad. He was promoted to the active roster on November 1.