Radiation-induced thyroiditis is a form of painful, acute thyroiditis resulting from radioactive therapy to treat hyperthyroidism or from radiation to treat head and neck cancer or lymphoma. It affects 1% of those who have received radioactive iodine (I-131) therapy for Graves' Disease, typically presenting between 5 and 10 days after the procedure.[1] Stored T3 and T4 are released as rapid destruction of thyroid tissue occurs which results in pain, tenderness, and exacerbation of hyperthyroidism. [2]
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