R. Kip Guy

R. Kip Guy
Born
Alabama, US
SpouseCaitlin Allen
Children2
Academic background
EducationBA, chemistry, Reed College
PhD, organic chemistry, 1996, Scripps Research
ThesisAn Exploration of the Chemistry of Taxo (1996)
Doctoral advisorK. C. Nicolaou
Academic work
InstitutionsUniversity of Kentucky College of Pharmacy
St. Jude Children's Research Hospital
University of California, San Francisco

R. Kip Guy is an American pharmaceutical chemist. As of 2016, he is the dean of the University of Kentucky College of Pharmacy.

Early life and education

Guy was born in Alabama but was raised in various places including Jacks Creek, Tennessee, England, and Ohio.[1] He completed his Bachelor of Arts degree in chemistry from Reed College before working as a process development chemist in the process translation unit at IBM Research. Following this, he received his PhD in organic chemistry in 1996 based on the total synthesis of taxol from the Scripps Research Institute.[2] His thesis was conducted under the guidance of K. C. Nicolaou and was titled An Exploration of the Chemistry of Taxol.[3] After this, Guy accepted a postdoctoral fellowship in cellular biology at the University of Texas Southwestern Medical Center and additional training in physiology at the Woods Hole Oceanographic Institution.[4]

Career

After completing his postdoctoral fellowship, Guy joined the University of California, San Francisco as an assistant professor with joint appointments in pharmaceutical chemistry and cellular and molecular pharmacology.[4] While there, he established an independent laboratory to develop strategies for targeting and signaling systems for testosterone and estrogen.[1] In 2005, Guy moved to St. Jude Children's Research Hospital to found and chair its new department of chemical biology and therapeutics as the Robert J. Ulrich Chair in Chemical Biology and Therapeutics.[5] While serving in this position, he led the anti-malarial drug-discovery effort and preclinical development of SJ733.[6]

In October 2016, Guy left St. Jude's to become the dean of the University of Kentucky College of Pharmacy.[7] While serving in this role, he continued his research from St. Jude studying blocking cancer-causing proteins on a cellular level. In 2017, his research team became the first to show that protein interaction controlled by N-terminal acetylation could be blocked.[8] Following this discovery, Guy was elected a Fellow of the American Association for the Advancement of Science (AAAS).[9]

Personal life

Guy and his wife, pediatric psychologist Caitlin Allen, have two children together.[2]

References

  1. ^ a b "LEARNING, LEGACIES, & HIS LABOR OF LOVE". September 8, 2016. Retrieved June 12, 2021.
  2. ^ a b "Spotlight: Kiplin Guy". CERN. May 2013. Retrieved June 12, 2021.
  3. ^ "ALUMNI PROFILES: Kip Guy". Scripps Research. Retrieved June 12, 2021.
  4. ^ a b "R. KIP GUY, PHD, TO SPEAK AT OHIO STATE DURING 2018 DISTINGUISHED LECTURE SERIES". Ohio State University. May 21, 2018. Retrieved June 11, 2021.
  5. ^ "R. Kip Guy, PhD". University of Kentucky. Retrieved June 14, 2021.
  6. ^ "St. Jude experimental anti-malarial drug shows promise in first clinical trial". Eurekalert. April 8, 2020. Retrieved June 14, 2021.
  7. ^ Perry, Allison (July 5, 2016). "UK College of Pharmacy Names New Dean". University of Kentucky. Retrieved June 14, 2021.
  8. ^ Colon, Kristie (June 26, 2017). "Blocking Cancer—Scientists Find New Way to Combat Disease". University of Kentucky. Retrieved June 14, 2021.
  9. ^ Colon, Kristie (December 4, 2019). "AAAS and University of Kentucky Announce 2019 Fellows". University of Kentucky. Retrieved June 14, 2021.

R. Kip Guy publications indexed by Google Scholar

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