Psychrobacter arcticus is a Gram-negative, nonmotile species of bacteria[1] first isolated from Siberian permafrost. Its type strain is 273-4T (=DSM 17307T =VKM B-2377T).[1]
Hypoacylated lipopolysaccharide (LPS) from P. arcticus induces weak TLR4-mediated inflammatory response in macrophages and such LPS bioactivity may potentially result in the failure of local and systemic bacterial clearance in patients.[2]
^Korneev, KV; Kondakova, AN; Arbatsky, NP; Novototskaya-Vlasova, KA; Rivkina, EM; Anisimov, AP; Kruglov, AA; Kuprash, DV; Nedospasov, SA; Knirel, YA; Drutskaya, MS (December 2014). "Distinct biological activity of lipopolysaccharides with different lipid A acylation status from mutant strains of Yersinia pestis and some members of genus Psychrobacter". Biochemistry. Biokhimiia. 79 (12): 1333–8. doi:10.1134/S0006297914120062. PMID25716726. S2CID2948187.
Further reading
Whitman, William B., et al., eds. Bergey's manual® of systematic bacteriology. Vol. 5. Springer, 2012.
Dworkin, Martin, and Stanley Falkow, eds. The Prokaryotes: Vol. 6: Proteobacteria: Gamma Subclass. Vol. 6. Springer, 2006.
Ponder, Monica A.; Thomashow, Michael F.; Tiedje, James M. (2008). "Metabolic activity of Siberian permafrost isolates, Psychrobacter arcticus and Exiguobacterium sibiricum, at low water activities". Extremophiles. 12 (4): 481–490. doi:10.1007/s00792-008-0151-0. ISSN1431-0651. PMID18335164. S2CID8536734.