Potosí or Potosi may refer to:

• Potosi, Missouri, in Washington County
• Potosi, Nevada, a ghost town in Clark County, Nevada
• Potosi, Texas, in Taylor County
• Potosi (town), Wisconsin, in Grant County
  • Potosi, Wisconsin, a village within the Town of Potosi

• Potosí, the capital of Potosí Department, Bolivia, a silver mining center and UNESCO World Heritage Site
• Potosí Department, a department in southwestern Bolivia
• Potosi, Venezuela, a disestablished town in Táchira
• San Luis Potosí City, capital and most populous city of San Luis Potosí, Mexico

• Potosi Mountain (Nevada), U.S.
• Potosí mountain range or Cordillera de Potosí, to the southeast of the city of Potosí, Bolivia
• Potosi Peak, in the Sneffels Range, Colorado, US
• Cerro de Potosí, a mountain near the city of Potosí, Bolivia, also known as Cerro Rico; a Spanish colonial mining site
• Cerro Potosí, a mountain in Nuevo León, Mexico
• Huayna Potosí, a mountain in the La Paz Department, Bolivia
• Wayna Potosí (Oruro), a mountain in the Oruro Department, Bolivia

• Potosi (barque), an 1895 German sailing ship named after the Bolivian city
• Potosi Correctional Center, a prison near Potosi, Missouri
• Potosi Mining District, in Clark County, Nevada
• Potosi, Trelawny, Jamaica, a former sugar plantation
• Potosi Pinyon (Pinus culminicola), a species of pine tree native to northeast Mexico
• Potosi pupfish (Cyprinodon alvarezi), a species of fish once endemic to Mexico, but now extinct in the wild

• Potosi Mine (disambiguation)
• Potosi Mountain (disambiguation)

This disambiguation page lists articles associated with the title Potosi.
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