Pioneer Building may refer to:

• Pioneer Building (San Francisco), listed on the NRHP in San Francisco, California
• Pioneer Building of the Pioneer and Endicott Buildings, Saint Paul, Minnesota, listed on the NRHP in Minnesota
• Montana Veterans and Pioneers Memorial Building, Helena, Montana, listed on the NRHP in Lewis and Clark County, Montana
• Pioneer Building (New Rochelle, New York), listed on the NRHP in Westchester County, New York
• Pioneer Building (Oklahoma City, Oklahoma), listed on the NRHP in Oklahoma County, Oklahoma
• Pioneer Building (Seattle, Washington), listed on the NRHP in Washington
• Pioneer Block, Eau Claire, Wisconsin, listed on the NRHP in Eau Claire County, Wisconsin

• Pioneer Hall (disambiguation)
• Pioneer Mine Buildings and A Headframe, Ely, Minnesota, listed on the NRHP in St. Louis County, Minnesota
• Pioneer Theater-Auditorium, Reno, Nevada, listed on the NRHP in Washoe County, Nevada
• Ghirardelli Square, which includes Pioneer Woolen Mills and D. Ghirardelli Company, San Francisco CA, listed on the NRHP in San Francisco, California

This disambiguation page lists articles associated with the title Pioneer Building.
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