After his father's death in 1472, his mother became regent. Philibert was betrothed to Bianca Maria Sforza, daughter of Galeazzo Maria Sforza of Milan, by his second wife, Bona of Savoy, in 1474.[a][2] They had no children.
Initially kidnapped by Savoyard noblemen and held at Turin, the intervention of Louis XI of France led to Philibert's release.[3] He died from tuberculosis, in Lyons, at the age of 17 and the duchy was inherited by his younger brother Charles.[3]