After graduating college he went to work at the Taiwan Textile Research Institute before finding work in a dyeing and finishing plant. He then went abroad to the United States for postgraduate work at Kansas State University in 1981, completing over 500 credits in a variety of subjects including mathematics, physics, and chemistry.[3]
After receiving his doctorate in materials science, Tsai went to teach and work at the University of Tennessee.[3][6] In total, he holds 12 U.S. patents and over 20 commercial license agreements.[6] Tsai retired from the University of Tennessee in 2019.[10] He was a professor in the Department of Material Science and Engineering.[6]
In 1992 while at the University of Tennessee, Tsai led a team attempting to improve electrostatic filtration manufacturing.[3][7] The material consists of both positive and negative charges, which are better able to attract particles — such as dust, bacteria and viruses — and trap them by polarization before they can pass through the mask.[3][4] It was patented in the U.S. in 1995.[4][6][7][12]
Tsai continued to do work into mask technology and in 2018 he developed a new technique which doubled the filtration capacity of medical masks.[10]
^ abNote: In spite of the claims made by sources cited in this biography on Tsai's N95 involvement, please refer to the N95 respirator article for more information. The N95 is a 42 CFR Part 84 standard, effective July 10, 1995. Citations to support Tsai's work follow:[2][3][4]