Fazzini was born on 4 May 1913 at Grottammare, in the province of Ascoli Piceno in the Marche, to Vittorio Fazzini and Maria Alessandrini. As a boy he worked with his brothers in the family carpentry workshop, where he learned to carve wood. In 1930, with the help of the poet Mario Rivosecchi, he moved to Rome to study at the Scuola libera del nudo.[4][5]
He started work on his large bronze La Resurrezione for the new Aula Paolo VI in the Vatican City in 1970, although he was not formally commissioned to make it until 1972. It was completed and inaugurated in 1977. A maquette is on display in the Vatican Museums.[6]