Patuxent may refer to:

• Patuxent people, an Algonquian people indigenous to what is now the Mid-Atlantic United States

• Patuxent, Maryland, an unincorporated community in Charles County
• Patuxent Ice Stream, between the Patuxent Range and Pecora Escarpment
• Patuxent Range, a mountain chain in Antarctica
• Patuxent River, Maryland
• Patuxent Wildlife Research Center, a U.S. Fish and Wildlife Service facility in Beltsville, Maryland
• Naval Air Station Patuxent River, an installation of the United States Navy in St. Mary's County, Maryland
• Calvert County, Maryland, once known as Patuxent County
• Woodwardville, Maryland, an unincorporated community known as Patuxent from 1927 to the 1980s

• Patuxent River stone, the state gem of Maryland
• USS Patuxent (AT-11), sea-going tugboat in commission with the United States Navy from 1909 to 1924
• USS Patuxent (AO-44), an oiler in commission with the United States Navy from 1942 to 1946
• USNS Patuxent (T-AO-201), a fleet replenishment oiler in service with the United States Navy since 1995.

This disambiguation page lists articles associated with the title Patuxent.
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