Born in La Spezia, Masini started his career on Genoa youth system.[2] He was loaned to Serie C club Sambenedettese for the 2020–21 season, and made his professional debut on 27 September 2020 against Carpi.[3]
On 29 January 2021, he was loaned to Lecco for the rest of the season.[4] He renewed his loan for the next season.[5]
After appearing two times on Genoa's bench early in the 2022–23 season, on 1 September 2022 Masini was loaned by Novara.[6]
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