PXK

PX domain containing serine/threonine kinase
Identifiers
SymbolPXK
Alt. symbolsFLJ20335, MONaKA
NCBI gene54899
HGNC23326
OMIM611450
RefSeqNM_017771
UniProtQ6ZN39
Other data
LocusChr. 3 p21.2
Search for
StructuresSwiss-model
DomainsInterPro

PX domain containing serine/threonine kinase also known as PXK is a protein which in humans is encoded by the PXK gene.[1][2]

Function

PXK binds to the Na⁺/K⁺-ATPase beta-1 (ATP1B1) and beta-3 (ATP1B3) subunits and modulates both Na⁺/K⁺-ATPase enzymatic and ion pump activities.[2]

See also

References

  1. ^ "Entrez Gene: PX domain containing serine/threonine kinase".
  2. ^ a b Mao H, Ferguson TS, Cibulsky SM, Holmqvist M, Ding C, Fei H, Levitan IB (August 2005). "MONaKA, a novel modulator of the plasma membrane Na,K-ATPase". J. Neurosci. 25 (35): 7934–43. doi:10.1523/JNEUROSCI.0635-05.2005. PMC 6725465. PMID 16135750.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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