It is the second track on the first side of the LP album and was released as its second single. The song is very instrumentally based, with numerous bass and guitar riffs and a long instrumental introduction. The vocals start after 56 seconds. At the start of the song, a man can be heard saying something in Spanish. It is commonly believed to be the Spanish phrase, "Salpica Micaela," said by José "Chepito" Areas himself to the other musicians about the style (rhythm or "feel") to play the song. The song is famous for its "call and response" passage between the guitar and the bass.
In a 50-year retrospective on the album and the song No One to Depend On, Glide Magazine opined;[2]
Apart from Rolie’s sensuous singing—hear especially “No One to Depend On–”most of the insinuating dynamics much in the music derives from Michael Shrieve’s versatility at his drum kit. His alternately delicate and utterly abandoned touch is altogether reminiscent of his solo as highlighted in the Woodstock movie.