Muse began his college career at William & Mary. As a freshman, he caught four passes for 55 yards and one touchdown.[2] Muse was named third-team All-Colonial Athletic Association as a sophomore after finishing the season with 30 receptions for 453 yards and one touchdown. After the season, he transferred to South Carolina.[3]
Muse caught 17 passes for 158 yards in his first season with the Gamecocks.[4] As a senior, he had 30 receptions for 425 yards and one touchdown.[5] Muse decided to utilize the extra year of eligibility granted to college athletes who played in the 2020 season due to the coronavirus pandemic and return to South Carolina for a third season.[6] He caught 20 passes for 222 yards with two touchdowns in his final season.[7]
Muse was drafted by the Minnesota Vikings with the 227th overall pick in the seventh round of the 2022 NFL draft.[10] He was waived on August 30, 2022, and re-signed to the practice squad one day later.[11][12] Muse was signed to the 53-man roster on November 19, 2022.[13] He was waived on January 6, 2023, and re-signed to the practice squad.[14] He signed a reserve/future contract on January 16, 2023.[15]
Muse was released on November 26, 2024, and re-signed to the practice squad.