Zadegan was born on June 20, 1982, in Heidelberg, Baden-Württemberg, West Germany, and raised in the San Francisco Bay Area.[3] She is of Iranian heritage.[3]
In 2009, Zadegan appeared in the Persian language stage production of From Satellite with Love "Az Mahvareh Ta Eshgh", touring in the U.S. and Europe.[4]
In 2009, Zadegan played 'The Leper' in Rajiv Joseph's Bengal Tiger at the Baghdad Zoo, which moved to Broadway in 2011.[5][6] The same year she portrayed the First Lady turned president, Dalia Hassan, in the FOX series 24.[7]
Zadegan appeared in the 2010 film Elena Undone in the title role of Elena Winters for FilmMcQueen.[8] That same year she also appeared opposite Michael Sheen and Samuel L. Jackson in the role of Jehan Younger in the Columbia TriStar psychological thriller Unthinkable.
Zadegan returned to television as resident villainess Isabel on the NBC series The Event.[1] She then took on the series regular role of Dr. Gina Bandari on the 2012 series Emily Owens M.D.[9] She appeared as Scarlet Leon, the female lead, opposite Greg Kinnear in the 2014 American version of the comedy Rake.[10]
Later that same year she rounded out the all female-lead cast for Bravo's first scripted series Girlfriends' Guide to Divorce in the role of Delia Banai. The show went on to be the first ever to get a three-season pickup and ran for five seasons before premiering its final season in Spring 2018.[11]
In 2015 Zadegan continued to appear in other television series such as Extant, Legends and as the Queen of Iran opposite Michael Sheen for Showtime's critical success Masters of Sex.
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Martinez, Jose (April 2010). "Necar Zadegan: A Force of Nature". Venice Magazine. Archived from the original on March 9, 2012. Retrieved April 25, 2021 – via Wayback Machine, Internet Archive.