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National Institutes of Health Director's Pioneer Award is a research initiative first announced in 2004 designed to support individual scientists' biomedical research. The focus is specifically on "pioneering" research that is highly innovative and has a potential to produce paradigm shifting results. The awards, made annually from the National Institutes of Health common fund, are each worth $500,000 per year, or $2,500,000 for five years.^[1]

Source: NIH

• Larry Abbott
• George Q. Daley
• Homme W. Hellinga
• Joseph McCune
• Steven L. McKnight
• Rob Phillips
• Stephen R. Quake
• Chad Mirkin
• Xiaoliang Sunney Xie

Source: NIH

• Vicki L. Chandler
• Hollis T. Cline
• Leda Cosmides
• Titia de Lange
• Karl Deisseroth
• Pehr A.B. Harbury
• Erich D. Jarvis
• Thomas A. Rando
• Derek J. Smith
• Giulio Tononi
• Clare M. Waterman-Storer
• Nathan Wolfe
• Junying Yuan

Source: NIH

• Kwabena A. Boahen
• Arup K. Chakraborty
• Lila M. Gierasch
• Rebecca W. Heald
• Karla Kirkegaard
• Thomas J. Kodadek
• Cheng Chi Lee
• Evgeny A. Nudler
• Gary J. Pielak
• David A. Relman
• Rosalind A Segal
• James L. Sherley
• Younan Xia

Source: NIH

• Lisa Feldman Barrett
• Peter Bearman
• Emery N. Brown
• Thomas R. Clandinin
• James J. Collins
• Margaret Gardel
• Takao K. Hensch
• Marshall S. Horwitz
• Rustem F. Ismagilov
• Frances E. Jensen
• Mark J. Schnitzer
• Gina Turrigiano

Source: NIH

• James K. Chen, Ph.D., Stanford University
• Ricardo Dolmetsch, Ph.D., Stanford University
• James Eberwine, Ph.D., University of Pennsylvania
• Joshua M. Epstein, Ph.D., Brookings Institution
• Bruce A. Hay, Ph.D., California Institute of Technology
• Ann Hochschild, Ph.D., Harvard Medical School
• Charles M. Lieber, Ph.D., Harvard University
• Barry London, M.D., Ph.D., University of Pittsburgh
• Tom Maniatis, Ph.D., Harvard University
• Teri W. Odom, Ph.D., Northwestern University
• Hongkun Park, Ph.D., Harvard University
• Aviv Regev, Ph.D., Massachusetts Institute of Technology/Broad Institute
• Aravinthan D.T. Samuel, Ph.D., Harvard University
• Saeed Tavazoie, Ph.D., Princeton University
• Alice Y. Ting, Ph.D., Massachusetts Institute of Technology
• Alexander van Oudenaarden, Ph.D., Massachusetts Institute of Technology

Source: NIH

• Ivor J. Benjamin, University of Utah School of Medicine
• Ajay Chawla, Stanford University
• Chang-Zheng Chen, Stanford University
• Hilde Cheroutre, La Jolla Institute for Immunology
• Markus W. Covert, Stanford University
• Joseph M. DeSimone, University of North Carolina at Chapel Hill/North Carolina State University
• Sylvia M. Evans, University of California, San Diego
• Joseph R. Fetcho, Cornell University
• Timothy E. Holy, Washington University School of Medicine
• Tannishtha Reya, Duke University
• Gene E. Robinson, University of Illinois at Urbana-Champaign
• Susan M. Rosenberg, Baylor College of Medicine
• Leona D. Samson, Massachusetts Institute of Technology
• Nirao M. Shah, University of California, San Francisco
• Krishna V. Shenoy, Stanford University
• Sarah A. Tishkoff, University of Pennsylvania
• Alexander J. Travis, Cornell University State College of Veterinary Medicine
• Jin Zhang, Johns Hopkins University School of Medicine

Source: NIH

• Carlos F. Barbas III, Ph.D., Scripps Research
• Pamela J. Bjorkman, Ph.D., California Institute of Technology
• Valentin Dragoi, Ph.D., University of Texas, Health Science Center at Houston
• Stephen W. Fesik, Ph.D., Vanderbilt University School of Medicine
• Tamas L. Horvath, D.V.M., Ph.D., Yale School of Medicine
• J. Keith Joung, M.D., Ph.D., Massachusetts General Hospital / Harvard Medical School
• David Kleinfeld, Ph.D., University of California, San Diego
• Haifan Lin, Ph.D., Yale University
• Jun O. Liu, Ph.D., Johns Hopkins University School of Medicine
• Andres Villu Maricq, M.D., Ph.D., University of Utah
• Joseph H. Nadeau, Ph.D., Institute for Systems Biology
• Miguel A. L. Nicolelis, M.D., Ph.D. , Duke University
• Lalita Ramakrishnan, M.D., Ph.D., University of Washington
• Lorna W. Role, Ph.D., Stony Brook University
• Michael L. Roukes, Ph.D., California Institute of Technology
• Ram Samudrala, Ph.D., University of Washington
• Bruce A. Yankner, M.D., Ph.D., Harvard Medical School

Source: NIH

• Utpal Banerjee, Ph.D., University of California, Los Angeles
• Brenda L. Bass, Ph.D., University of Utah
• Jean Bennett, Ph.D., University of Pennsylvania
• William M. Clemons, Ph.D., California Institute of Technology
• Florian Engert, Ph.D., Harvard University
• Andrew P. Feinberg, M.D., M.P.H., Johns Hopkins University
• James E.K. Hildreth, M.D., Ph.D., University of California, Davis
• Tao Pan, Ph.D., University of Chicago
• Sharad Ramanathan, Ph.D., Harvard University
• David S. Schneider, Ph.D., Stanford University
• Thanos Siapas, Ph.D., California Institute of Technology
• Andreas S. Tolias, Ph.D. , Baylor College of Medicine
• Mehmet Fatih Yanik, Ph.D. , Massachusetts Institute of Technology

Source: NIH

• Anne Brunet, Ph.D., Stanford University
• Edward Marcotte, Ph.D., University of Texas at Austin
• Hidde Ploegh, Ph.D., Whitehead Institute
• Christina Smolke, Ph.D., Stanford University
• Yi Tang, Ph.D., University of California
• Doris Ying Tsao, Ph.D., California Institute of Technology,
• Lihong V. Wang, Ph.D., Washington University in St. Louis
• Chao-Ting Wu, Ph.D., Harvard University Medical School
• Gary Yellen, Ph.D., Harvard University Medical School
• Feng Zhang, Ph.D., Broad Institute

Source: NIH

• Amy Arnsten, Ph.D., Yale University, New Haven, CT
• Edward S. Boyden, Ph.D., Massachusetts Institute of Technology, Boston, MA
• Vadim N. Gladyshev, Ph.D., Brigham and Women's Hospital and Harvard Medical School, Boston, MA
• Baljit S. Khakh, Ph.D., University of California Los Angeles, David Geffen School of Medicine, CA
• Michael Z. Lin, M.D., Ph.D., Stanford University, Stanford, CA
• Jay Shendure, M.D., Ph.D., University of Washington, Seattle, WA
• Natalia A. Trayanova, Ph.D., The Johns Hopkins University, Baltimore, MD
• Fan Wang, Ph.D., Duke University Medical Center, Durham, NC
• Leor S Weinberger, Ph.D., Gladstone Institutes and University of California, San Francisco, CA
• Xiaoliang Sunney Xie, Ph.D., Harvard University, Cambridge, MA
• Rafael Yuste, M.D., Ph.D., Columbia University, New York, NY
• Mark J Zylka, Ph.D., University of North Carolina, Chapel Hill, NC

Source: NIH

• Jayakrishna Ambati, M.D., University of Kentucky
• Chenghua Gu, D.V.M., Ph.D., Harvard medical School
• Cato T. Laurencin, M.D., Ph.D., University of Connecticut
• Denise J. Montell, Ph.D., University of California Santa Barbara
• Carl D. Novina, M.D., Ph.D., Dana-Farber Cancer Institute
• Amy Palmer, Ph.D., University of Colorado
• Dana Pe'er, Ph.D., Columbia University
• Oliver Rando, M.D., Ph.D. , University of Massachusetts Medical School
• Donna L. Spiegelman, Sc.D., Harvard School of Public Health
• Sean Wu, M.D., Ph.D., Stanford University

Source: 2015 NIH

• Giovanni Bosco, Dartmouth Geisel School of Medicine
• Jeffery S. Cox, University of California San Francisco
• Matthew David Disney, The Scripps Research Institute
• Zemer Gitai, Princeton University
• Jonathon Howard, Yale University
• Craig Montell, University of California Santa Barbara
• Coleen T. Murphy, Princeton University
• Gwendalyn J. Randolph, Washington University School of Medicine
• Steven J. Schiff, The Pennsylvania State University
• Hao Wu, Boston Children’s Hospital and Harvard Medical School
• Tony Wyss-Coray, Stanford University School of Medicine and VA Palo Alto
• Ryohei Yasuda, Max Planck Florida Institute for Neuroscience
• Sheng Zhong, University of California San Diego

Source: NIH

• Kristin Baldwin, The Scripps Research Institute
• Bradley Bernstein, Massachusetts General Hospital and Broad Institute
• Michael Fischbach, University of California, San Francisco
• Uri Hasson, Princeton University
• Juan Carlos Izpisua Belmonte, The Salk Institute for Biological Studies
• Nancy Kanwisher, Massachusetts Institute of Technology
• Stephen D. Liberles, Harvard Medical School
• Christine Mayr, Memorial Sloan Kettering Cancer Center
• Joshua D. Rabinowitz, Princeton University
• Meng Wang, Baylor College of Medicine
• Sing Sing Way, Cincinnati Children’s Hospital
• Seok-Hyun "Andy" Yun, Massachusetts General Hospital and Harvard Medical School

Source: NIH

• Hongjie Dai, Stanford University
• Amit Etkin, Stanford University
• Howard A. Fine, Weill Cornell College of Medicine
• Charles M. Lieber, Harvard University
• Jeffrey D. Macklis, Harvard University
• Luciano A. Marraffini, Rockefeller University
• Alex Schier, Harvard University
• Ramin Shiekhattar, University of Miami
• David A. Sinclair, Harvard Medical School
• Justin L. Sonnenburg, Stanford University
• Kay M. Tye, MIT
• Feng Zhang, Broad Institute, MIT

Source: NIH

• Janelle S. Ayres, Salk Institute
• Daniel A. Colón-Ramos, Yale University School of Medicine
• Christina Curtis, Stanford University School of Medicine
• Viviana Gradinaru, Caltech
• Jonathan Kipnis, University of Virginia School of Medicine
• Hyungbae Kwon, Max Planck Florida Institute for Neuroscience
• Michelle Monje, Stanford University
• Gabriel D. Victora, Rockefeller University
• Amy J. Wagers, Harvard Medical School
• Peng Yin, Harvard University

Source: NIH

• Mark Andermann, Beth Israel Deaconess Medical Center, Harvard Medical School
• James Eberwine, University of Pennsylvania Perelman School of Medicine
• Jennifer H. Elisseeff, Johns Hopkins University
• Valentina Greco, Yale University
• Christophe Herman, Baylor College of Medicine
• Sun Hur, Boston Children’s Hospital
• Rob Knight, University of California San Diego
• Jin Hyung Lee, Stanford University
• Marina R. Picciotto, Yale University
• Hidde Ploegh, Boston Children's Hospital, Harvard Medical School
• Simon Scheuring, Weill Cornell Medicine

Source: NIH

• Annelise E. Barron, Stanford University, Schools of Medicine and of Engineering
• Kathleen Collins, University of California at Berkeley
• Christopher D. Harvey, Harvard Medical School
• Peter S. Kim, Stanford University
• Brian Litt, University of Pennsylvania
• Shu-Bing Qian, Cornell University
• Susan M. Rosenberg, Baylor College of Medicine
• John Schoggins, University of Texas Southwestern Medical Center
• David Veesler, University of Washington School of Medicine
• Magdalena Zernicka-Goetz, California Institute of Technology and University of Cambridge

• List of medicine awards

• Official website