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(a) SCF contains three core subunits—the RING protein Rbx1, the cullin Cul1, and Skp1. Rbx1 binds the E2–ubiquitin conjugate. The target protein binds to an F-box protein that is bound to the enzyme core via interactions with the Skp1 subunit. After binding of a target protein to the F-box protein, the ubiquitin is transferred from E2 and attached via a peptide bond to a lysine side chain in the target protein. (b) A composite model structure for human SCF derived from X-ray structures of...

Changan CS75InformasiProdusenChang'an MotorsMasa produksi2013–sekarangBodi & rangkaKelasSUV crossover kompakBentuk kerangkaSUV 5 pintuTata letakMesin depan, penggerak roda depan Changan CS75 (Hanzi: 长安CS75, bahasa Rusia: Чанган CS75) adalah crossover kompak yang diproduksi oleh Chang'an Motors. Memulai debutnya pada Guangzhou Auto Show 2013 dan diluncurkan di pasar mobil Tiongkok pada tahun 2014, Changan CS75 asli menerima facelift pada tahun 2018 dan model PHEV t...

Hospital in Maryland USA, founded 1979 Hospital in Maryland, U.S.Adventist HealthCare Shady Grove Medical CenterAdventist HealthCareGeographyLocationRockville, Maryland, U.S.OrganisationCare systemAdventist HealthCareServicesBeds266[1]HistoryOpened1979LinksWebsiteadventisthealthcare.com/locations/profile/shady-grove-medical-center/ListsHospitals in U.S. Part of a series onSeventh-dayAdventist Church History Christianity Protestantism Millerism Great Disappointment 1888 General Confere...

Roman Catholic archbishop (born 1948) His EminenceJohn DewArchbishop Emeritus of WellingtonDew in 2014ArchdioceseWellingtonAppointed24 May 2004 (coadjutor)Installed21 March 2005Term ended5 May 2023PredecessorThomas WilliamsSuccessorPaul MartinOther post(s)Cardinal-Priest of Sant'IppolitoOrdersOrdination9 May 1976by Reginald DelargeyConsecration31 May 1995by Thomas WilliamsCreated cardinal14 February 2015by Pope FrancisRankCardinal PriestPersonal detailsBorn (1948-05-05) 5 May 1948 (...

Japanese Second ArmyJapanese Troops in the Battle of ShahoActiveSept 1894-Aug 1945　Country Empire of JapanBranch Imperial Japanese ArmyTypeInfantryRoleCorpsNickname(s)Ikioi (勢, Vigorous)EngagementsFirst Sino-Japanese WarRusso-Japanese WarSecond Sino-Japanese WarWorld War IIMilitary unit Japanese 2nd Army (24 May 1904)Parent unitSouthern Expeditionary Army GroupComponents 1st Infantry Division 3rd Infantry Division 4th Infantry Division Japanese 2nd Army (15 August 1945)Parent un...

Moscow Metro station PaveletskayaПавелецкаяMoscow Metro stationGeneral informationLocationZamoskvorechye DistrictCentral Administrative OkrugMoscowRussiaCoordinates55°43′50″N 37°38′16″E / 55.7305°N 37.6377°E / 55.7305; 37.6377Owned byMoskovsky MetropolitenLine(s) Zamoskvoretskaya linePlatforms1 island platformTracks2ConnectionsTram: A, 3, 38, 39Bus: Б (along the Garden ring), 913, с920, с932. Night routes: н8.ConstructionStructure typePyl...

Aire d'attraction de Souillac Localisation de l'aire d'attraction de Souillac dans le département du Lot. Géographie Pays France Régions Nouvelle-Aquitaine - Occitanie Départements Lot - Dordogne Caractéristiques Type Aire d'attraction d'une ville Code Insee 521 Catégorie Aires de moins de 50 000 habitants Nombre de communes 11 soit 10 (Lot) + 1 (Dordogne) Population 8 351 hab. (2021) modifier  L'aire d'attraction de Souillac est un zonage d'étude défini par ...

Kaunas (berasal dari nama Slavia Kovno) ialah kota terbesar di Lituania. Pada 1441 kota ini bergabung dengan Liga Hanseatik. Kota ini menjadi tempat klahiran Boris Kotzin, Aleksandr Postnikov, Emma Goldman dan Aleksandr Mikhailovich Nedoshivin. Menjadi pusat kongres SAT pada 1992. Nama kota Nama Kovno berasal dari nama Polandia Kowno. Tokoh terkenal Valdas Adamkus, presiden terkini Lituania. Wikimedia Commons memiliki media mengenai Kaunas.

Nat Turner ditangkap oleh Mr. Benjamin Phipps, seorang petani lokal Nat TurnerLahirNat (Turner)(1800-10-02)2 Oktober 1800Southampton County, VirginiaMeninggal11 November 1831(1831-11-11) (umur 31)Jerusalem, VirginiaSebab meninggalEksekusi hukum gantungKebangsaanAmerikaDikenal atasPemberontakan Nat TurnerSuami/istriCherry[1] Nat Turner (2 Oktober 1800 - 11 November 1831) adalah seorang budak Afrika-Amerika yang memimpin pemberontakan budak di Virginia pada 21 Agustus 1831 yan...

Thiệu TrịKaisar VietnamSebuah maklumat kekaisaran yang dikeluarkan oleh Thiệu Trị.Berkuasa1841–1847PendahuluMinh MạngPenerusTự ĐứcKelahiran16 Juni 1807Phú Xuân, Đại NamKematian4 November 1847(1847-11-04) (umur 40)Phú Xuân, Đại NamPemakamanXương LăngWangsaDinasti NguyễnNama dan tanggal periodeThiệu Trị (紹治): 1841–1847Nama anumertaThiệu thiên Long vận Chí thiện Thuần hiếu Khoan minh Duệ đoán Văn trị Võ công Thánh triết ...

Stephano (satelit) adalah satelit alami dari planet Uranus. Uranus, adalah sebuah planet ketujuh dari Tata Surya, memiliki 27 bulan yang diketahui, yang semuanya dinamai karakter dari karya-karya William Shakespeare dan Alexander Pope. Referensi http://solarsystem.nasa.gov/planets/profile.cfm?Object=Uranus&Display=Moons Diarsipkan 2014-07-28 di Wayback Machine.

Book by James P. O'Donnell This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: The Bunker book – news · newspapers · books · scholar · JSTOR (March 2021) (Learn how and when to remove this message) The Bunker AuthorsJames P. O'DonnellUwe BahnsenOriginal titleDie Katakombe – Das Ende in der Reichskanz...

American musician For the 2nd-century BCE Jewish high priest of the Maccabees, see Mattathias. MatisyahuBackground informationBirth nameMatthew Paul MillerBorn (1979-06-30) June 30, 1979 (age 44)West Chester, Pennsylvania, U.S.OriginWhite Plains, New York, U.S.Genres Reggae hip hop alternative hip hop alternative rock[1] Occupation(s) Singer rapper Instrument(s) Vocals beatboxing Years active2000–presentLabelsThirty TigersThe OrchardEpicFallen SparksGreensleeves RecordsJDubSony...

German punitive operation in Belarus and Russia during World War II This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Operation Winterzauber – news · newspapers · books · scholar · JSTOR (February 2016) (Learn how and when to remove this message) Operation WinterzauberPart of Bandenbekämpfung in German-occupi...

Commuter rail station in Denver, Colorado 41st & Fox B   G 41st & Fox stationGeneral informationOther names41st•FoxLocation4105 North Fox StreetDenver, ColoradoCoordinates39°46′23″N 104°59′48″W / 39.77306°N 104.99667°W / 39.77306; -104.99667Owned byRegional Transportation DistrictLine(s)Northwest Corridor[1]Platforms1 island platformTracks2ConstructionStructure typeAt-gradeParking500 spacesAccessibleYesHistoryOpenedApr...

United Nations resolution adopted in 2006 UN Security CouncilResolution 1704UNMIT policeDate25 August 2006Meeting no.5,516CodeS/RES/1704 (Document)SubjectThe situation in East TimorVoting summary15 voted forNone voted againstNone abstainedResultAdoptedSecurity Council compositionPermanent members China France Russia United Kingdom United StatesNon-permanent members Argentina Rep. of the Congo Denmark Ghana Greece Japan Peru ...

761-й окремий розвідувальний артилерійський полк Нарукавний шеврон полкуНа службі -2004Країна  Радянський Союз → Україна  УкраїнаВид Сухопутні військаТип  Ракетні війська і артилеріяЧисельність полкУ складі Північне оперативне командуванняБазування в/ч ...

American physicist Marissa GiustinaGiustina in 2019Alma materThayer School of Engineering University of ViennaScientific careerInstitutionsQuantum Artificial Intelligence LabThesisCharacterizing photoresponse in black silicon at excitation below the silicon bandgap (2010) Marissa Giustina is an American physicist who is a senior research scientist at the Quantum Artificial Intelligence Lab. Her research considers the development of quantum computing and experimental tests of quantum...

Serie B d'Eccellenza maschile FIP 2000-2001Dettagli della competizioneSport Pallacanestro OrganizzatoreLNP Federazione FIP Periodosettembre 2000 —giugno 2001 Squadre28  (in 2 gironi) VerdettiPromozioni Celana Bergamo Pall. Pavia C.S. Borgomanero B.C. Ferrara Orlandina Sutor Montegranaro Retrocessioni Pall. Cagliari Azzurra Brindisi Cronologia della competizioneed. successiva →     ← ed. precedente Modifica dati su Wikid...

مقاطعة ووكر     الإحداثيات 33°48′13″N 87°17′52″W / 33.803611111111°N 87.297777777778°W / 33.803611111111; -87.297777777778   [1] تاريخ التأسيس 26 ديسمبر 1823  سبب التسمية جون وليامز ووكر  تقسيم إداري  البلد الولايات المتحدة[2]  التقسيم الأعلى ألاباما  العاصمة جاسبر[3] ...