After Italia '90 and after an attempt by Brian Clough to sign Lorenzo for Nottingham Forest fell through, Argentine legend Ossie Ardiles signed the defender for Swindon Town on loan and eventually the deal became a permanent switch. He played 27 times for The Robins, scoring two goals: one in his debut at the County Ground against Portsmouth in a 3–0 win, and one away at Watford in a 2–2 draw.
After retiring, Lorenzo joined José Pékerman's staff in the Argentina national under-20 team in 2000, as an assistant coach. He worked with Carlos Aimar at Spanish side CD Leganés under the same role, before reuniting with Pékerman in the Argentina national team in 2004.
On 16 December 2020, Lorenzo had his first managerial experience after being named at the helm of Peruvian Primera División side FBC Melgar.[4] After a poor start in the Fase 1, as the club finished in the last position of their group, they finished fourth in the Fase 2 and qualified to the 2022 Copa Sudamericana.
Under Lorenzo's guidance, Melgar won the 2022 Apertura tournament in July.[5] He left after qualifying the club to the quarterfinals of the Copa Sudamericana.[6]
Colombia national team
On 2 June 2022, the Colombian Football Federation announced Lorenzo as head coach of the national team for the following four years;[7] he remained in charge of Melgar until July.[8] On 20 June 2023, Colombia beat the Germany national team for the first time in its history in a dominant 2–0 victory under Lorenzo.[9]
In July 2024, Colombia went 28 games undefeated under Lorenzo and had significant victories over the national teams of Germany, Brazil, Uruguay and Spain.[10] Another major achievement of Lorenzo's was leading the national team to its first Copa America final in 23 years and managing Colombia to score 12 goals in the 2024 Copa America, their highest record in the competition;[11] they lost the final on extra time to Argentina.