Mylius-Erichsen Land is bounded in the north by the Independence Fjord, in the west by the Hagen Fjord and the Hagen Glacier, in the east by the Danmark Fjord and in the south by the Greenland Ice Sheet. There is no large calving glacier at the head of the Danmark Fjord, but all surrounding fjords are icebound the whole year round.
The northernmost headland is Cape Rigsdagen and the northern section of the peninsula appears in some maps as "Valdemar Glückstadt Land."