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"My Lucille" is a 1985 song written for the 1985 John Landis film called Into the Night, starring Jeff Goldblum and Michelle Pfeiffer. It was written by Ira Newborn and recorded by B.B. King. The title of the song is a reference to B.B. King's guitars. The song was used in the movie while Ed Okin (Jeff Goldblum) walks through the night club.

The music video for the song was directed by John Landis, and was broadcast as part of the television documentary film B.B. King "Into the Night". The video features Goldblum, Pfeiffer, Dan Aykroyd from Into the Night, and Steve Martin and Eddie Murphy.

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