My Brother's Keeper may refer to:

• "My brother's keeper", a phrase from the biblical story of Cain and Abel
• My Brother's Keeper (Davenport novel), by Marcia Davenport
• My Brother's Keeper (Sheffield novel), by Charles Sheffield
• My Brother's Keeper, a 2005 novel by Patricia McCormick
• My Brother's Keeper, a book by Bo Gritz
• My Brother's Keeper, a book by Stanislaus Joyce, brother of James Joyce
• My Brother's Keeper, a series of Star Trek books by Michael Jan Friedman
• My Brother's Keeper, a comic book published by Spire Christian Comics
• My Brother's Keeper: A History of the American Jewish Joint Distribution Committee 1929–1939, a book by Yehuda Bauer
• My Brother's Keeper: A Memoir and a Message, a book by Amitai Etzioni
• My Brother's Keeper, a play by Nigel Williams

• My Brother's Keeper (film), a 1948 British film starring Jack Warner
• My Brother's Keeper, a 1995 TV film featuring Ellen Burstyn
• My Brother's Keeper (Le Sang du frère), a 2004 film starring Christian Potenza
• My Brother's Keeper, a 2020 short film about the reunion of Guantanamo prisoner Mohamedou Ould Slahi and his former guard Steve Wood

• My Brother's Keeper (TV series), a 1975–1976 British sitcom
• "My Brother's Keeper", an episode of Bonanza
• "My Brother's Keeper" (Danny Phantom episode), an episode of Danny Phantom
• "My Brother's Keeper", an episode of ER
• "My Brother's Keeper", an episode of Everwood
• "My Brother's Keeper", an episode of The Fresh Prince of Bel-Air
• "My Brother's Keeper", an episode of G.I. Joe: A Real American Hero
• "My Brother's Keeper", an episode of Gunsmoke
• "My Brother's Keeper" (Lucifer), an episode of Lucifer
• "My Brother's Keeper", an episode of NCIS: New Orleans
• "My Brother's Keeper" (The Punisher), an episode of The Punisher
• "My Brother's Keeper" (Sliders), a 1999 episode of Sliders
• "My Brother's Keeper", an episode of Tales from the Crypt
• "My Brother's Keeper" (The Vampire Diaries), a 2012 episode of The Vampire Diaries

• My Brother's Keeper (Long Live G), an EP by DaBaby, 2020
• My Brother's Keeper (K-Ci and JoJo album), 2013
• My Brother's Keeper (Lake album), 2006
• My Brother's Keeper (OuterSpace album), 2011
• "My Brother's Keeper", a song by Ying Yang Twins from U.S.A. (United State of Atlanta), 2005

• My Brother's Keeper Challenge

• Am I My Brother's Keeper, an album by Kane & Abel, 1998
• Brother's keeper (disambiguation)
• Her Brother's Keeper (disambiguation)
• His Brother's Keeper (disambiguation)
• My Sister's Keeper (disambiguation)

This disambiguation page lists articles associated with the title My Brother's Keeper.
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