The museum in housed within an 1878 hôtel particulier by architect Nicolas Félix Escalier, formerly owned by the painter Guillaume Dubufe, acquired by Henner's niece in 1921. It was inaugurated as a museum in 1924, under the direction of Henner's former pupil Many Benner; it became a national museum in 1943. Today the museum contains a large collection of paintings and drawings by Alsatian painter Jean-Jacques Henner, including some 1,000 sketches, documents and souvenirs distributed in seven rooms on four floors of exhibition space. The collection includes more than 130 portraits, as well as mythical themes and figures in dream landscapes that approached Symbolism. Many studies are displayed with finished paintings, together with descriptions by major critics of the day.