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Mucometrocolpos

Mucometrocolpos is the abnormal accumulation of genital secretions (mucus) that occur as a result of an imperforate hymen and the buildup of these secretions behind the hymen. The secretions originate from uterine and cervical glands.[1] It is a rare, congenital condition and usually occurs independent of other abnormal structures though inheritance can play a part in its occurrence. It also occurs with McKusick–Kaufman syndrome (MKS). Polydactyly and heart disease are associated with this condition. Diagnosis is challenging because symptoms also occur in a variety of other syndromes.[2] Secretions can build up and extend as far as the uterus and abdomen.[3] Mucometrocolpos can sometimes cause abdominal distention.[4] The build up of mucous secretions can occur prior to adolescence unrelated to menstruation.[5] Many cases can be detected prenatally.[6][1] Treatment is surgical and is specific for each case. After treatment, many females are still able to conceive and carry a pregnancy to term.[1]

References

  1. ^ a b c Dosedla, Erik; Kacerovsky, Marian; Calda, Pavel (2011-03-01). "Prenatal diagnosis of hydrometrocolpos in a down syndrome fetus". Journal of Clinical Ultrasound. 39 (3): 169–171. doi:10.1002/jcu.20785. ISSN 1097-0096. PMID 21387330. S2CID 11211408.
  2. ^ Yapar, E. G.; Ekici, E.; Aydogdu, T.; Senses, E.; Gökmen, O. (1996-12-18). "Diagnostic problems in a case with mucometrocolpos, polydactyly, congenital heart disease, and skeletal dysplasia". American Journal of Medical Genetics. 66 (3): 343–346. doi:10.1002/(SICI)1096-8628(19961218)66:3<343::AID-AJMG19>3.0.CO;2-M. ISSN 0148-7299. PMID 8985498.
  3. ^ Babcock, Diane S. (January 1989). Neonatal and pediatric ultrasonography. Churchill Livingstone. ISBN 9780443086069.
  4. ^ Saclarides, Theodore J.; Myers, Jonathan A.; Millikan, Keith W. (2015-01-02). Common Surgical Diseases: An Algorithmic Approach to Problem Solving. Springer. ISBN 9781493915651.
  5. ^ Kaiser, Georges L. (2012-12-13). Symptoms and Signs in Pediatric Surgery. Springer Science & Business Media. ISBN 9783642311611.
  6. ^ Stevenson, Roger E. (2015-10-27). Human Malformations and Related Anomalies. Oxford University Press. ISBN 9780199386031.


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