The Moon High football team competes in the WPIAL Class AAAAA Allegheny Six Conference, which is made up of South Fayette, Baldwin, Upper St. Clair, Bethel Park, and Peters Township.[5]
In 2003 the team beat Thomas Jefferson 2–1 to win the WPIAL AA Championship. In the semi-final game before the championship, Moon beat Mars 2–0.[8]
Girls' soccer
The Moon High girls' soccer team won the PIAA AA state title in 2012.
The Moon High girls' soccer team won the PIAA AAA state title in 2016, 2017 and 2022.[9]
The Moon High girls' soccer team won the PIAA AAAA state title in 2021.[10]
Girls' rugby
The Moon High girls' rugby team won the RugbyPA D2 state title in 2017.[11]
The Moon High girls' rugby team won the RugbyPA D1 state title in 2022.[12]
Swimming and diving
The Moon boys' swimming team won the state championship in 1980, and the girls' team won state titles in 1996 and 1997.[13]
Boys' basketball
The Moon High boys' basketball team made school history, winning three consecutive WPIAL championships – 2004, 2005, 2006. The team was crowned state champions in 2004.[14]
In the 2006–2007 season, Moon entered the WPIAL Class AAAA, but went back down to WPIAL Class AAA in the 2008–2009 season.[15]
Moon boys' varsity basketball won the WPIAL 5A final March 1, 2017 and won the PIAA 5A final March 22, 2019.
Moon boy's varsity basketball won the WPIAL 5A final March 1, 2024, their fifth in school history.
Girls' basketball
The Moon High ladies' basketball team won the 2002 and 2005 WPIAL championship. The Lady Tigers have also reached the final four of the PIAA state playoffs multiple times.[16]
Gymnastics
The gymnastics team has won the 2008, 2012, 2013, 2014, 2017, 2018, 2022 and 2023 WPIAL district championships.