It shows the Virgin Mary on a high throne in a mosaic-decorated apse, while offering a hand towards the bowing Saints Cosmas and Damian.[1] A bearded Saint John the Baptist, in a sleeveless vest, is portrayed on the left. On the right, the Christ Child is blessing Saint Apollonia (whose attribute of the pincer with tooth is in the plinth before her), Saint Catherine of Alexandria (with her attribute, the broken wheel), and Saint John the Evangelist (with a book). An angel sits at the foot of the throne in the centre foreground and holds a stringed musical instrument.