Houser attended the Columbus Blue Jackets' 2016 training camp but was not signed. He instead signed with the team's AHL affiliate, the Cleveland Monsters on October 14.[10][11] Aside from a lone appearance with the Monsters, Houser spent the majority of the season with the Cyclones.
Houser once again attended an NHL training camp the following season, this time for the Arizona Coyotes. He was released on September 18,[12] but spent the season with their affiliates (the AHL's Tucson Roadrunners and ECHL's Fort Wayne Komets).[13]
As the Cyclones goaltender for the 2018–19 season, Houser had a 29–7–5 record in 41 games. He was named ECHL Goaltender of the Year[14] as well as a member of the league's first all-star team.[15]
On September 11, 2020, the Rochester Americans re-signed Houser to a one-year contract.[16] He remained on the Americans' roster as the Cyclones—an affiliate of the Americans—opted out of the 2020–21 season due to the COVID-19 pandemic.[17] On March 19, 2021, the Buffalo Sabres signed Houser to a one-year contract for the remainder of the season.[18] He subsequently spent time on the team's taxi squad.[19] Houser made his NHL debut on May 3, stopping 34 shots in a 4–2 win over the New York Islanders. Speaking about making the NHL and winning his first game, he stated "I've worked my whole life for this, for it to happen. Just to play a game is really special. But to win, winning is always the goal. That's why we play."[20] Houser started a second-straight game against the Islanders the following night, this time making 45 saves in a 4–3 shootout win.[21]
As a free agent following his stint with the Sabres, Houser continued within the organization in agreeing to a one-year contract to remain with the Rochester Americans on August 5, 2021.[22] With the Sabres suffering a spate of goaltender injuries for the second consecutive season, Houser was signed to a one-year, two-way contract in returning to the NHL with Buffalo on January 12, 2022.[23]
On July 15, 2022, Houser was familiarly re-signed to remain within the Sabres organization, agreeing to a one-year AHL contract to continue with the Rochester Americans.[24]
Houser returned for his fifth season in the Americans organization, signing as a free agent from the Sabres on a one-year AHL contract on July 7, 2023.[25]