In the film, a sexually transmitted disease called STBO is sweeping the country; it spreads by sex without emotional involvement, and most of its victims are young people who have sex out of curiosity rather than commitment. A woman hires two men to steal the serum, which has been locked away in a pharmaceutical company's offices.
Plot
In the Paris of the not-too-distant future, a mysterious disease, STBO, is killing people who have sex without emotional involvement. A serum has been developed, but it is locked away out of the reach of those who need it. An American woman blackmails two aging crooks, Marc and Hans, into stealing it. Marc recruits Alex, a rebellious teenager whose father worked for him before his death. Alex has a girlfriend, Lise, but falls for Marc's lover, Anna.
Julie Delpy has said she came out of filming this movie traumatized: "It was a very difficult shoot. I had a motorcycle accident. In order to make the insurance work, I wasn't taken to the doctor right away. As a result, my leg became gangrenous—one more day and it was amputation. Moreover Leos Carax was not easy. The actress was not easy either."[4]