A product of the São Paulo youth academy, Antônio started his career in the lower divisions of Brazilian football. In 2014, he played for Juventus-SP in Paulista A3. In June of the same year, he signed for Portimonense in Segunda Liga.[3]
Antônio made his first team debut against Covilhã.[4] On 1 October 2014, he scored his first goal for the club as Portimonense defeated Porto B 2–0.[5]
On 1 August 2017, Antônio transferred to Urawa Red Diamonds in Japan. On 30 November, he was named in the side's 23-man squad for the 2017 FIFA Club World Cup.[6][7] He was the tournament's top goalscorer (alongside Romarinho and Cristiano Ronaldo) despite playing only one game[2] and being eliminated in the second round.[8]