Matthew Keeslar was born in Grand Rapids, Michigan, the son of Fred Keeslar and Ann Ferguson, who divorced in 1977.[1]
He attended the acting program at the Juilliard School. While a student there, he played the title role in a touring production of Molière's Don Juan, directed by Joseph Chaiken; produced and starred in a student production of Waiting for Godot; and participated in several interdepartmental productions. He was part of the Drama Division's Group 24, graduating in 1995.[citation needed]
Keeslar retired from acting in 2010, citing financial difficulties and a lack of work, and went on to pursue a career in science. He wrote an essay about his struggles with his acting career and subsequent decision to enroll at Portland Community College.[3] He graduated Phi Beta Kappa from Reed College with a biology degree in May 2014. His biology thesis explored the effects of antimalarials on the brains of frogs.[4]