In 2016, Karp's first book, This Vast Southern Empire: Slaveholders at the Helm of American Foreign Policy, was published by Harvard University Press and went on to win several awards.[1][2][4] The book examines how slavery shaped U.S. foreign relations before the Civil War.[2] Karp is currently writing a book titled The Radicalism of the Republican Party, which examines the emergence of anti-slavery politics in the United States and in particular the radical vision of the Republican Party in the 1850s before the Civil War.[1][2][4]