Lohrei decided to return to the Buckeyes for the 2022–23 season. He finished second on the team in assists, and third in total points, with 28 and 32, respectively. Ohio State would make the NCAA tournament, but would lose in the second round to the eventual champion Quinnipiac Bobcats.
Professional
Boston Bruins
On March 31, 2023, the Providence Bruins announced that they had signed Lohrei to an amateur tryout contract for the remainder of the 2022–23 season, ending his collegiate career.[3] He played in five regular season games with the club, registering one assist. He would also play in three playoff games, before the Bruins were eliminated by the Hartford Wolf Pack.
Lohrei started the 2023–24 season with Providence.[4] However, it would not take long for him to receive a call-up to the NHL, as injuries to the Bruins defense corps caused him to make his NHL debut on November 2, 2023, against the Toronto Maple Leafs, where he also recorded his first NHL point, an assist on a goal by Pavel Zacha. With his debut, Lohrei became the first NHL player born in the state of Louisiana. He would score his first NHL goal a few games later against the Dallas Stars on November 6, 2023. Lohrei impressed in his first NHL stint, but was sent back down to Providence on November 25, 2023, following the injury recovery of Matt Grzelcyk.[5] It wouldn't take long for him to return to the NHL club, however, as he would return on December 7, 2023. Lohrei stayed with Boston until being sent down on January 20, 2024, once again due to Bruins defense Derek Forbort being fit to play.[6] In his return to the NHL on February 21, 2024, Lohrei scored three assists against the Edmonton Oilers. Lohrei was once again sent back down to the AHL on April 12, 2024.[7] On April 23, 2024, Lohrei was called back up to the Bruins, and made his NHL playoff debut in Game 3 of the first round against the Toronto Maple Leafs,[8] and scored his first NHL playoff point in the following game, an assist on a goal by James van Riemsdyk. After the Bruins eliminated the Leafs in seven games, Lohrei scored his first NHL playoff goal in Game 1 of the second round against the Florida Panthers.