Mary Claire may refer to:

• Mary Claire Engstrom (1906–1997), American writer and historian
• Mary Claire Helldorfer, American young adult- and children's author
• Mary Hogg (born 1947), British lawyer and former High Court judge
• Mary-Claire King (born 1946), American geneticist
• Mary-Claire Carter, fictional character in the UK medical drama TV series Holby City
• Mary Jean St. Claire, American contestant on The Amazing Race (American TV series)

• Marie Claire
• Mary Clare (disambiguation)

Topics referred to by the same term

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