Mark Lathrop
Canadian Biostatistician (born 1950)
Mark Lathrop (born 1950) is a Canadian Biostatistician . He headed the Center for the Study of Human Polymorphisms , but returned to Canada as Scientific Director at McGill University and Genome Quebec's Innovation Centre in 2011.[ 1]
Bibliography
Hung, Rayjean J; McKay James D; Gaborieau Valerie; et al. (April 2008). "A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25" (PDF) . Nature . 452 (7187): 633–7. Bibcode :2008Natur.452..633H . doi :10.1038/nature06885 . hdl :2318/102453 . PMID 18385738 . S2CID 4418808 .
Moffatt, Miriam F; Kabesch Michael; et al. (July 2007). "Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma" (PDF) . Nature . 448 (7152): 470–3. Bibcode :2007Natur.448..470M . doi :10.1038/nature06014 . hdl :2027.42/62682 . PMID 17611496 . S2CID 4373589 .
Bouzigon, Emmanuelle; Corda Eve; Aschard Hugues; Dizier Marie-Hélène; Boland Anne; Bousquet Jean; Chateigner Nicolas; Gormand Frédéric; Just Jocelyne; Le Moual Nicole; Scheinmann Pierre; Siroux Valérie; Vervloet Daniel; Zelenika Diana; Pin Isabelle; Kauffmann Francine; Lathrop Mark; Demenais Florence (November 2008). "Effect of 17q21 variants and smoking exposure in early-onset asthma" . N. Engl. J. Med. 359 (19): 1985–94. doi :10.1056/NEJMoa0806604 . PMID 18923164 .
Spanagel, Rainer; Pendyala Gurudutt; Abarca Carolina; Zghoul Tarek; Sanchis-Segura Carles; Magnone Maria Chiara; Lascorz Jesús; Depner Martin; Holzberg David; Soyka Michael; Schreiber Stefan; Matsuda Fumihiko; Lathrop Mark; Schumann Gunter; Albrecht Urs (January 2005). "The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption" (PDF) . Nat. Med. 11 (1): 35–42. doi :10.1038/nm1163 . ISSN 1078-8956 . PMID 15608650 . S2CID 11106714 .
Kathiresan, S; Willer; Peloso; Demissie; et al. (December 2008). "Common variants at 30 loci contribute to polygenic dyslipidemia" . Nat. Genet. 41 (1): 56–65. doi :10.1038/ng.291 . PMC 2881676 . PMID 19060906 .
McKay, James D; Hung Rayjean J; et al. (December 2008). "Lung cancer susceptibility locus at 5p15.33" . Nat. Genet. 40 (12): 1404–6. doi :10.1038/ng.254 . PMC 2748187 . PMID 18978790 .
Barrett, Jeffrey C; Hansoul Sarah; et al. (August 2008). "Genome-wide association defines more than thirty distinct susceptibility loci for Crohn's disease" . Nat. Genet. 40 (8): 955–62. doi :10.1038/ng.175 . PMC 2574810 . PMID 18587394 .
Saar Kathrin; et al. (The STAR Consortium) (May 2008). "SNP and haplotype mapping for genetic analysis in the rat" . Nat. Genet. 40 (5): 560–6. doi :10.1038/ng.124 . PMC 5915293 . PMID 18443594 .
Willer, Cristen J; Sanna, S; Jackson, AU; Scuteri, A; Bonnycastle, LL; Clarke, R; Heath, SC; Timpson, NJ; et al. (February 2008). "Newly identified loci that influence lipid concentrations and risk of coronary artery disease" . Nat. Genet. 40 (2): 161–9. doi :10.1038/ng.76 . PMC 5206900 . PMID 18193043 .
Wellcome Trust Case Control Consortium; Australo-Anglo-American Spondylitis Consortium (TASC); Burton, PR; Clayton, DG; Cardon, LR; Craddock, N; Deloukas, P; Duncanson, A; et al. (November 2007). "Association scan of 14,500 nsSNPs in four common diseases identifies variants involved in autoimmunity" . Nat. Genet. 39 (11): 1329–37. doi :10.1038/ng.2007.17 . PMC 2680141 . PMID 17952073 .
Dixon, Anna L; Liang Liming; Moffatt Miriam F; Chen Wei; Heath Simon; Wong Kenny C C; Taylor Jenny; Burnett Edward; Gut Ivo; Farrall Martin; Lathrop G Mark; Abecasis Gonçalo R; Cookson William O C (October 2007). "A genome-wide association study of global gene expression". Nat. Genet. 39 (10): 1202–7. doi :10.1038/ng2109 . PMID 17873877 . S2CID 13182548 .
Menzel, Stephan; Garner Chad; Gut Ivo; Matsuda Fumihiko; Yamaguchi Masao; Heath Simon; Foglio Mario; Zelenika Diana; Boland Anne; Rooks Helen; Best Steve; Spector Tim D; Farrall Martin; Lathrop Mark; Thein Swee Lay (October 2007). "A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15". Nat. Genet. 39 (10): 1197–9. doi :10.1038/ng2108 . PMID 17767159 . S2CID 19615925 .
Fischer, Judith; Lefèvre Caroline; Morava Eva; Mussini Jean-Marie; Laforêt Pascal; Negre-Salvayre Anne; Lathrop Mark; Salvayre Robert (January 2007). "The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy". Nat. Genet. 39 (1): 28–30. doi :10.1038/ng1951 . ISSN 1061-4036 . PMID 17187067 . S2CID 23679419 .
Delmaghani, Sedigheh; del Castillo Francisco J; Michel Vincent; Leibovici Michel; Aghaie Asadollah; Ron Uri; Van Laer Lut; Ben-Tal Nir; Van Camp Guy; Weil Dominique; Langa Francina; Lathrop Mark; Avan Paul; Petit Christine (July 2006). "Mutations in the gene encoding pejvakin, a newly identified protein of the afferent auditory pathway, cause DFNB59 auditory neuropathy". Nat. Genet. 38 (7): 770–8. doi :10.1038/ng1829 . ISSN 1061-4036 . PMID 16804542 . S2CID 2443891 .
Sakuntabhai, Anavaj ; Turbpaiboon, C; Casadémont, I; Chuansumrit, A; Lowhnoo, T; Kajaste-Rudnitski, A; Kalayanarooj, SM; Tangnararatchakit, K; et al. (May 2005). "A variant in the CD209 promoter is associated with severity of dengue disease" . Nat. Genet. 37 (5): 507–13. doi :10.1038/ng1550 . ISSN 1061-4036 . PMC 7096904 . PMID 15838506 .
Auwerx, Johan; Avner, P; Baldock, R; Ballabio, A; Balling, R; Barbacid, M; Berns, A; Bradley, A; et al. (September 2004). "The European dimension for the mouse genome mutagenesis program" . Nat. Genet. 36 (9): 925–7. doi :10.1038/ng0904-925 . ISSN 1061-4036 . PMC 2716028 . PMID 15340424 .
Gut, Ivo G; Lathrop G Mark (August 2004). "Duplicating SNPs". Nat. Genet. 36 (8): 789–90. doi :10.1038/ng0804-789 . ISSN 1061-4036 . PMID 15284844 . S2CID 20840537 .
Allen, Maxine; Heinzmann Andrea; Noguchi Emiko; Abecasis Gonçalo; Broxholme John; Ponting Chris P; Bhattacharyya Sumit; Tinsley Jon; Zhang Youming; Holt Richard; Jones E Yvonne; Lench Nick; Carey Alisoun; Jones Helene; Dickens Nicholas J; Dimon Claire; Nicholls Rosie; Baker Crystal; Xue Luzheng; Townsend Elizabeth; Kabesch Michael; Weiland Stephan K; Carr David; von Mutius Erika; Adcock Ian M; Barnes Peter J; Lathrop G Mark; Edwards Mark; Moffatt Miriam F; Cookson William O C M (November 2003). "Positional cloning of a novel gene influencing asthma from chromosome 2q14". Nat. Genet. 35 (3): 258–63. doi :10.1038/ng1256 . ISSN 1061-4036 . PMID 14566338 . S2CID 40595323 .
Caulfield, Mark; Munroe Patricia; Pembroke Janine; Samani Nilesh; Dominiczak Anna; Brown Morris; Benjamin Nigel; Webster John; Ratcliffe Peter; O'Shea Suzanne; Papp Jeanette; Taylor Elizabeth; Dobson Richard; Knight Joanne; Newhouse Stephen; Hooper Joel; Lee Wai; Brain Nick; Clayton David; Lathrop G Mark; Farrall Martin; Connell John (June 2003). "Genome-wide mapping of human loci for essential hypertension". Lancet . 361 (9375): 2118–23. doi :10.1016/S0140-6736(03)13722-1 . PMID 12826435 . S2CID 6625775 .
References
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