Verdú was born in Madrid, Spain. She began acting at 13, appearing in various commercials. She left school at the age of 15, so that she could fully devote herself to her acting career. Verdú has appeared in more than 60 movies, since 1984, the majority of them in Spanish. She has also been on numerous TV shows.
Her first work experience was as a model in spots and fashion magazines for known commercial firms. Her first television opportunity was given to her at 13, featuring in the anthology series La huella del crimen,[1] directed by Vicente Aranda in the episode "Captain Sánchez's Crime".
She made her feature film debut in El sueño de Tánger at age 14, starring alongside Fabio Testi.[1] Shot in 1985, the film underwent a production hell,[2] and was not released until 1991. Her first appearance in a theatrical release was thus in the 1986 film El orden cómico.[3]
Verdú's performance in drama Lucky Star (1997) earned her another goya award nomination; she played one-eyed pregnant Marina, in a love triangle with a gelded butcher and a handsome criminal.[4]
She made her debut in an international work in Y tu mamá también (2001),[5] portraying Luisa Cortés, an exotic madrileña who ends up accepting a trip offer across rural Mexico from a Mexican cousin-in-law and his friend.[6] In 2002, she starred as the title character in comedy peplumLisístrata, playing an Athenian woman setting up a sex strike.[7] She was cast against type to portray maid and guerrilla informant Mercedes in Pan's Labyrinth (2006).[8][9] Verdú was invited to membership in the AMPAS in 2007.[10] Verdú's performance in Seven Billiard Tables (2007) earned Verdú her first Goya Award for Best Actress.[11]
Verdú's portrayal of Encarna (the evil stepmother) in black-and-white and silent drama film Snow White (2012) won her a second Goya Award.[13]
In 2017, she appeared in Abracadabra, starring as Carmen, a housewife who sees her husband's personality transformed as a result of an informal hypnosis session.[14]
She made her theater debut in 1986, starring as the character of Julieta and has since then combined theater with cinema. She has also intertwined the two in television shows, such as Turno de oficio and Segunda enseñanza.
In 2018, she starred in comedy film Empowered, portraying Paz, an undervalued middle-aged woman who stops keeping quiet about things,[15] and in black comedy Crime Wave as Leyre, a housewife covering the murder of her son's father, unleashing a wave of crimes.[16] She also portrayed Agatha, a villainess from planet Chitón, in superhero comedy film Superlópez, based on the comic book character of the same name.[17]
In 2020, she began shooting legal thriller television series ANA. all in, her first acting credit in television since her work in Código fuego (2003).[18] She starred as Ana Tramel, a drug-addicted lawyer who turns in after her gambling brother is accused of murder in a casino.[19]
In March 2021, she was cast as Barry Allen/The Flash's mother Nora Allen in the DC Extended Universe film The Flash,[20] which was released in June 2023. She also appeared as eccentric millionaire Olivia Uriarte in whodunit film A Deadly Invitation.[21] She also portrayed Carmen, a toxic mother and bon vivant, in season 7 of teen drama series Elite,[22] and the girlfriend and advisor of Leo (Daniel Giménez Cacho) in Familia.[23]