Initially it comprised the former Piedmontese provinces of Alessandria, Casale, Tortona, Voghera and Bobbio. Following the annexation of the Ligurian Republic to France in 1805, Voghera, Bobbio and Tortona passed to the newly created Department of Genoa, while the Department of Marengo acquired Asti, previously in the Department of Tanaro.
Its population in 1812 was 318,447, and its area was 348,261 hectares.[1]
The division was included within the 28th military division, the 16th cohort of the légion d'honneur, the 29th conservation des forêts, the Diocese of Casale, the sénatorerie of Turin and the court of appeal of Genoa. It elected three deputies to the Corps législatif of the First Empire.