Makedones Thessalonikis F.C. (Greek: Γ.Σ Μακεδόνες Θεσσαλονίκης), the Macedonians, is a professional football club based in Ampelokipoi, Thessaloniki, Greece.

The club, originally named MAKEDON, was founded in 1987 from the merger of Megas Alexandros FC. .

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