MRCP has been slowly replacing endoscopic retrograde cholangiopancreatography (ERCP) as investigation of choice. MRCP is highly accurate in diagnosing the biliary system, pancreatic duct and accessing surrounding solid organs. Several advantages offered by MRCP is its non-invasive nature, less costly, requires less examination time when compared to ERCP (30 minutes), fewer staff required, and does not require any ionising radiation.[1][2][3][4]
Subject is needed to fast for at least four hours to ensure the biliary system is maximally distended with fluid while keeping the fluid in the gastrointestinal system at a minimum.[1] However, clear fluid and routine medication is allowed before the scan.[1] Negative oral contrast such as pineapple juice,[1] date syrup, ferumoxsil, Açaí juice and water are useful in decreasing T2 signal intensity, thus minimising signals from stomach and duodenum from interfering with signals from the biliary system.[6]
MRCP makes use of heavily T2-weighted MRI pulse sequences.[3][7] These sequences show high signal in static or slow moving fluids within the gallbladder, biliary ducts and pancreatic duct, with low signal of surrounding tissue. Secretin is also given to a patient to increase ductal compliance, making imaging easier.[3]
^Hekimoglu K, Ustundag Y, Dusak A, et al. (August 2008). "MRCP vs. ERCP in the evaluation of biliary pathologies: review of current literature". Journal of Digestive Diseases. 9 (3): 162–9. doi:10.1111/j.1751-2980.2008.00339.x. PMID18956595. S2CID25726694.