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MRPS9
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3J9M
Identifiers
Aliases	MRPS9, MRP-S9, RPMS9, S9mt, mitochondrial ribosomal protein S9
External IDs	OMIM: 611975; MGI: 1916777; HomoloGene: 32565; GeneCards: MRPS9; OMA:MRPS9 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	105,099,960 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	42,944,843 bp
RNA expression pattern
	Top expressed in
	myocardium of left ventricle; ; gastrocnemius muscle; ; deltoid muscle; ; tibialis anterior muscle; ; quadriceps femoris muscle; ; vastus lateralis muscle; ; muscle of thigh; ; apex of heart; ; mucosa of transverse colon; ; Skeletal muscle tissue of rectus abdominis;
	Top expressed in
	Paneth cell; ; medullary collecting duct; ; atrioventricular junction; ; fossa; ; atrioventricular valve; ; soleus muscle; ; condyle; ; endocardial cushion; ; myocardium of ventricle; ; epithelium of lens;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; structural constituent of ribosome; RNA binding;
Cellular component	mitochondrial inner membrane; ribosome; nucleolus; mitochondrial small ribosomal subunit; mitochondrion;
Biological process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); mitochondrial translational elongation; mitochondrial translational termination; protein biosynthesis;
	Sources:Amigo / QuickGO
Orthologs
	64965
	69527
	ENSG00000135972
	ENSMUSG00000060679
	P82933
	Q9D7N3
	NM_182640
	NM_023514
	NP_872578
	NP_076003
	Wikidata
View/Edit Human	View/Edit Mouse

Mitochondrial ribosomal protein S9 (MRPS9), otherwise known as uS9m, is a protein that in humans is encoded by the MRPS9 gene. ^[5]

Function

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. [provided by RefSeq, Jul 2008].

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000135972 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000060679 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Mitochondrial ribosomal protein S9". Retrieved 2018-02-11.

External links

Overview of all the structural information available in the PDB for UniProt: P82933 (Human 28S ribosomal protein S9, mitochondrial (MRPS9)) at the PDBe-KB.