In 1944, the IS-1 heavy tank saw it's debut at the town. 5 were knocked out by Panthers.
Until 18 July 2020, Lysianka served as an administrative center of Lysianka Raion. The raion was abolished in July 2020 as part of the administrative reform of Ukraine, which reduced the number of raions of Cherkasy Oblast to four. The area of Lysianka Raion was merged into Zvenyhorodka Raion.[3][4]
Until 26 January 2024, Lysianka was designated urban-type settlement. On this day, a new law entered into force which abolished this status, and Lysianka became a rural settlement.[5]