Lymphomatoid papulosis (LyP) is a rare skin disorder.
The overall prevalence rate of lymphomatoid papulosis is estimated at at least 1.2 cases per 1,000,000 population.[1] This rare condition has only been studied in depth since 1968.[2]
It can appear very similar to anaplastic large cell lymphoma.[3] Type "A" is CD30 positive, while type "B" is CD30 negative.[4]
It has been described as "clinically benign but histologically malignant."[5]
It may respond to methotrexate or PUVA.[7]
It can evolve into lymphoma.[8]
aggressive: Sézary disease
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