Luis Castillo may refer to:

• Luis Castillo (American football) (born 1983), Dominican-American NFL defensive end
• Luis Castillo (second baseman) (born 1975), Dominican Major League Baseball second baseman
• Luis Castillo (pitcher, born 1992) (born 1992), Dominican Major League Baseball pitcher
• Luis Castillo (pitcher, born 1995) (born 1995), Dominican Major League Baseball pitcher
• Luis Castillo (Ecuadorian boxer), boxer from Ecuador
• Luis Castillo (musician), keyboard player and backup vocalist for American rock band P.O.D.
• Luís Leandro Castillo (born 1991), Argentine footballer

• Luis del Castillo Estrada (born 1931), Uruguayan cleric
• José Luis Castillo (born 1973), boxer from Mexico
• José Luis Castillo (activist) (born 1968)

Topics referred to by the same term

This disambiguation page lists articles about people with the same name.
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