In July 2006, he was signed by Italian Serie B club Piacenza. He scored 5 league goals in the first season, ranked 5th of the team, as the team third strikers, behind Daniele Cacia and Daniele Degano. In the next season, after Cacia was sold (himself remained in Piacenza due to injury), he became the only central forward in the starting XI, but soon the coach preferred Houssine Kharja as the emergency striker, Julien Rantier and Giuseppe Gemiti in supporting role. In mid-October (round 11), he returned to starting XI until Cacia recovered (round 15). In January 2008, Cacia returned to Fiorentina and Kharja was sold, but the club signed Zlatko Dedič (loan) and Alessandro Tulli, made Simón remained as the third striker.
On 1 July 2009, Simón returned to Emilia. He had to compete with Tulli, Tomás Guzmán, Antonio Piccolo and Mattia Graffiedi for the remain place of supporting striker role in 4–3–3 formation, or as a backup central forward in 4–4–2 formation if Moscardelli was not available. The coach more frequently used Simone Guerra as supporting striker and Simón only made 8 start, 7 of them before the arrival of striker Edgar Çani in January.
In June 2010, he was loaned back to Argentina for Tigre.[2]
Unión La Calera
On 10 July 2011, Simón joined to Chilean Primera División club Unión La Calera for play the Clausura Tournament of that season, after of put end to his contract with Piacenza.[3] He netted a twice in his debut against Santiago Morning, scoring all goals of the game in a 2–0 home win.[4] On 17 September, he scored another twice for the team of La Calera, during an incredible 3–0 win over Chilean powerhouse Colo-Colo at Santa Laura. On 2 October, against Palestino, he again scored a goal, after of fail to score after two weeks against Audax Italiano and Unión Española. Simón was a key player in the qualification of his team to the playoffs, scoring on 20 November, two of the three goals of his team against Ñublense, in a 3–1 away victory at Nelson Oyarzún Arenas.