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There are many creatures in the mythology, folklore, and fiction of many cultures who are one-eyed, this page lists such one-eyed creatures.

In mythology, folklore and religion

Arimaspi, legendary people of northern Scythia, "always at war with their neighbours" and stealing gold from griffins. They had a single eye in the centre of the forehead.
Balor, a giant in Irish mythology, with one eye in his forehead that would wreak destruction when opened
Bungisngis, one-eyed giants of Philippine folklore
Cyclopes (singular: Cyclops), one-eyed giants in Greek mythology, including Polyphemus. They had a single eye in the centre of their forehead.
- Polyphemus, a giant Cyclops shepherd in Greek mythology
- Arges, one of the three Cyclops smith gods in Greek mythology
- Brontes, one of the three Cyclops smith gods in Greek mythology
- Steropes, one of the three Cyclops smith gods in Greek mythology
Dajjal, a figure in Islam akin to the Antichrist, who has one eye
Duwa Sokhor, an ancestor of Genghis Khan, according to The Secret History of the Mongols, who had one eye in his forehead^[1]
Fachan, a creature from Celtic mythology with one eye, one arm and one leg
The Eye of Providence is a representation of Divine Providence
The Graeae, the three witches (or sisters) that shared one eye and one tooth between them; often depicted as clairvoyant. They were forced by Perseus, by stealing their eye, into revealing the location of Medusa.
Hagen or Högni, a Burgundian warrior in German and Norse legend, depicted as one-eyed in some accounts
Some yokais, in the Japanese folklore, have a single giant eye:
- Hitotsume-kozō, monsters (obake) in Japanese folklore, with a single giant eye in the center of the face
- Hitotsume-nyūdō could pass for really tall human priests if not for the large, single eye in the center of their faces.
- Kasa-obake, one-eyed sentient umbrella yokai of Japanese folklore
- Shirime
- Yamawaro
Jian, a bird in Chinese mythology with only one eye and one wing. A pair of such birds were dependent on each other and inseparable.
Kabandha, a demon with no head or neck with one large eye on the breast and a mouth on the stomach. Kabandha appears in Hindu mythology as a character in the Ramayana.
Likho, an embodiment of evil fate and misfortune in Slavic mythology
Mapinguari, giant sloth-like cryptid of Brazil and Bolivia often described as having one eye
Odin, a Norse god (he was born with two eyes, but traded one for a drink from Mimir's well)
Ojáncanu, one-eyed giant with a ten-fingered hand, a ten-toed foot, a long beard and red hair of Cantabrian mythology who embodies evil, cruelty and brutality
One-Eye
- One of three sisters in the Brothers Grimm fairy tale One-Eye, Two-Eyes, and Three-Eyes
- A one-eyed giant in a story from a from Georgia, in the Caucasus, whose story parallels the story of Polyphemus (see Polyphemus#Possible origins)
Papinijuwari, Australian sky deities with vampiric tendencies
Popobawa, a Tanzanian shetani (evil spirit) that often takes the form of a one-eyed bat-like creature
Psoglav, a one-eyed dog-headed monster in Serbian mythology
Snallygaster, a one-eyed dragon-like creature said to inhabit the hills surrounding Washington, D.C. and Frederick County, Maryland
Tepegoz, a one-eyed ogre in the Oghuz Turkish epic Book of Dede Korkut
Ra, an Egyptian god whose right eye represents life, immortality, and light, often portrayed as a sun
Horus, an Egyptian god whose left eye represents the moon, healing, protection, and restoration

In fiction

Science fiction

Alpha Centauri, a green hermaphrodite hexapod with one huge eye; Doctor Who character first seen in The Curse of Peladon
Cylon Centurions in sci-fi franchise Battlestar Galactica
The Cyclops (1957), a science fiction horror film about a creature created via radiation exposure
Dalek Sec, a monster that became a one-eyed Dalek-human hybrid in Doctor Who
Gigan from the Godzilla series, a one-eyed alien cyborg Kaiju
Kerack, an alien race resembling large one-eyed prawns in the novel Camelot 30K
Magnus the Red, the one-eyed primarch of the Thousand Sons legion in Warhammer 40,000
Monoids, an alien race in the 1966 Doctor Who serial The Ark
Myo and other Abyssin aliens in Star Wars
Naga and his tribe of one-eyed violent mutants in the 1956 B-movie World Without End
Old One Eye, a unique Tyranid carnifex with the ability to rapidly regenerate from mortal wounds in Warhammer 40k
One-eyed, starfish-shaped aliens from the planet Paira in the 1956 Japanese film Warning from Space
Ravage, a panther-like Decepticon in Transformers: Revenge of the Fallen
Scaroth, last of the Jagaroth, a time-travelling alien in the 1979 Doctor Who story City of Death
Uniocs, an alien race in the webcomic Schlock Mercenary

Comic books

Basilisk, a large one-eyed mutant in Marvel Comics' New X-Men
Orb (comics), a Marvel Comics super-villain, primarily an adversary of Ghost Rider
Shuma-Gorath (or Shuma Gorath), a giant eye with tentacles in the Marvel comics universe, first appearance in Marvel Premiere #10 September 1973
Starro the Conqueror, a supervillain in DC Comics, a starfish-like creature who first appeared in 1960
Garagantos in Marvel Comics, first appearance in Sub-Mariner (1968–1974) issue #13

Historical and mythological fantasy

Beholder, a creature in the role-playing game Dungeons & Dragons with one large eye and many smaller eyestalks
Cyclops in the role-playing game Dungeons & Dragons
Draken, a one-eyed sea monster in the animated series Jumanji
Imbra, an idol and the highest god of Kafiristan in Rudyard Kipling's The Man Who Would Be King
Medusa in the Italian film Medusa Against the Son of Hercules, adapted for television as one episode of the series The Sons of Hercules
Rell, a cyclops in the film Krull. The Cyclops traded with the Beast one of their eyes for the ability to see into the future. The Beast did give them the ability to see into the future – but they can only see the moment of their own deaths.
Sauron, the eponymous arch-villain of The Lord of the Rings, often depicted as looking through a single 'Eye' in Peter Jackson's cinematic adaptations of Tolkien's work
Tyson, Percy Jackson's half-brother in Percy Jackson and the Olympians, is a Cyclops. Cyclopes also appear as villains.
Zargon, a giant one-eyed monster in the role-playing game Dungeons & Dragons

Animation and puppetry

Ahgg, the witches' giant spider with one eye in the center of his forehead in My Little Pony: The Movie
Some of the characters in Ben 10
Bill Cipher, an evil yellow eye of providence-like entity in Gravity Falls
Big Billy in The Powerpuff Girls who showed that he had one eye in the episode "School House Rocked"
B.O.B. (Bicarbonate Ostylezene Benzoate), a gelatinous creature in Monsters vs. Aliens
The Centaur Monster with a body of a centaur in TMNT (2007)
Horvak, Krumm's father from Aaahh!!! Real Monsters
Kang and Kodos, a recurring alien duo in the animated series The Simpsons
Leela, a mutant character, as well as her parents Munda and Morris, in the animated series Futurama. One episode also features the "Cyclopophage" - a one-eyed monster that only eats other one-eyed creatures (including the robot Bender, after one of his two eyes falls out).
Some of the Minions, comic henchmen in the Despicable Me franchise
Muno, a tall, red monster with one large eye, in the children's television series Yo Gabba Gabba!
Sheldon Plankton in the animated children's series SpongeBob SquarePants
Agent Pleakley in the 2002 animated film Lilo & Stitch
Sapphire in the Cartoon Network animated series Steven Universe
Mike Wazowski, a round monster with one large eye on the breast and a mouth on the stomach. He appears in the 2001 animated film Monsters, Inc.
Zatar the Alien, a green alien in the MTV series Celebrity Deathmatch
Tri-Klops, a henchman of the villain Skeletor in the children's show He-Man and the Masters of the Universe
Rob, an anthropomorph cyclop boy in the animated show The Amazing World of Gumball
Kyle, the owner of the Queen's Goiter, and Cloppy, Evan's one-eyed monster doll from The Barbarian and the Troll

Anime and manga

Lord Boros, in One-Punch Man, the alien leader of the Dark Matter Thieves, self-proclaimed subjugator of the universe, and the first antagonist to give Saitama a "serious fight"
Norman Burg, the butler and weapons specialist to Roger Smith in The Big O
Darklops Zero, prototype of Darklops in the film Ultraman Zero: The Revenge of Belial
Iwanaga Kotoko, in In/Spectre, A 17-year-old Goddess Of Wisdom to the spirits and humans alike, has only one eye and one leg due to sacrificing a part of her to become a goddess.
Manako, a cyclops sniper in Monster Musume
Hitomi Manaka, cyclops school nurse and protagonist of Nurse Hitomi's Monster Infirmary
Mannequin soldiers, lesser homunculi created by a government project in Fullmetal Alchemist

Video games

The beholster (a direct reference to the beholder from Dungeons & Dragons) in Enter the Gungeon
Ahriman, a species of monster from the Japanese role-playing game series Final Fantasy
The Cacodemon and Pain Elemental from id software's popular computer game DOOM
The Cyclops and other various monsters in the popular Japanese role-playing game series Dragon Quest
Dimitri Alexandre Blaiddyd from Fire Emblem: Three Houses
Drethdock from the Sega Saturn game Battle Monsters
The ghost Pokémon Duskull, Dusclops, and Dusknoir
Eggplant Wizard, an enemy in Nintendo's Kid Icarus
Evil Eye, a monster in the online RPG MapleStory
Fuyuhiko Kuzuryu, the ultimate yakuza from Danganronpa 2: Goodbye Despair.
Gohma in The Legend of Zelda has only one eye. Gohma's appearance varies from game to game.
Myukus a giant blue-green Alien with one eye in Rampage 2: Universal Tour
Suezo, a one-eyed, one-footed breed of monster in the video game/anime series Monster Rancher
Vaati and Bongo Bongo in the Legend of Zelda game series
Waddle Doo in Nintendo's game franchise Kirby

Music

Purple People Eater in the 1958 novelty song of the same name
Sgt. Psyclopps, the one-eyed guitarist for the costumed comedy punk band The Radioactive Chicken Heads
"Cyclops", a song from Portrait of an American Family by Marilyn Manson
Wotan/Wandrer in The Ring of the Nibelung, a Germanic variant of Odin in Wagner's cycle of four music-dramas
Black Shuck - a one-eyed demon dog in the song Black Shuck, by rock band The Darkness from their debut album Permission to Land.

Other

The Wicked Witch of the West from L. Frank Baum's The Wonderful Wizard of Oz; also other queens and witches in Oz such as Blinkie (The Scarecrow of Oz) and Marcia (The Yellow Knight of Oz).
Wenlock and Mandeville, London 2012 Olympic mascots
The mythological one-eyed creatures have also been the subject of many derivative works and adaptions.