Following is a list of notable defunct restaurants in Portland, Oregon:

• Acadia: A New Orleans Bistro
• Alexis Restaurant (1980–2016)
• Altabira City Tavern (2015–2020)
• Analog Café and Theater
• Arleta Library Bakery & Cafe
• Ataula (2013–2021)
• Aviary (2011–2020)
• Aviv (2017–2021)
• Baby Blue Pizza (2019–2022)
• Backspace
• Bailey's Taproom (2007–2021)
• Batterfish
• Beaker & Flask
• Beast (2007–2020)
• Berbati's Pan
• Berlin Inn (1992–2013)
• Bijou Cafe
• Bistro Agnes (2018–2022)
• Bit House Saloon (2015–2021)
• Biwa (2007–2018)
• Bluehour (2000–2020)
• Blueplate Lunch Counter and Soda Fountain (2006–2016)
• Bombay Cricket Club
• Botanist House (2018–2021)
• Brasserie Montmartre (1978–2006; 2009–2011; 2012–2015)
• Bridges Cafe (late 1990s – 2020)
• British Overseas Restaurant Corporation, formerly Saffron Colonial (2016–2019)
• Burger Stevens (2016–2024)
• Byways Cafe (1999–2019)
• Câche Câche
• Cafe Azul
• Caffe Mingo
• Candlelight Cafe & Bar (1984–2012)
• Canlis
• Carriage Room
• Castagna
• Century Bar (2016)
• Chez Machin (later Frog & Snail)
• Cicoria
• Circa 33 (2010–2021)
• Clyde Common (2007–2022)
• Country Bill's (1964–2012)
• Cup & Saucer Cafe (1980s–2022)
• Davis Street Tavern (2008–2016)
• Der Rheinlander (1963–2017)
• Dick's Kitchen (2010)
• Dig a Pony (2011–2022)
• Dime Store (2014–2015)
• Dóttir (2019–2022)
• Egyptian Club
• El Gallo Taqueria (2009–2022)
• Esparza's (1990–2014)
• Everybody Eats PDX
• Evoe
• Fat Head's Brewery
• Fenouil (2005–2011)
• Fermenter (2019–2024)
• Fish Grotto
• Fong Chong
• Genoa
• Georgian Room
• Gilt Club (2005–2014)
• The Goose
• Gotham Tavern
• Greek Cusina
• Grüner (2009–2015)
• Gypsy Restaurant and Velvet Lounge (1947–2014)
• Handsome Pizza (2012–2022)
• Henry Ford's Restaurant
• Henry Thiele Restaurant (1932–1990s)
• Hobo's
• Holy Trinity Barbecue (2019–2021)
• House of Louie
• Houston Blacklight
• Hunan Restaurant (1979–2014)
• Hung Far Low (1928–2015)
• Industrial Cafe and Saloon
• Irving Street Kitchen (2010–2020)
• Isabel Pearl
• JaCiva's Bakery and Chocolatier (1986–2024)
• Jackknife Bar (2014–2020)
• Kenny & Zuke's Delicatessen
• Kornblatt's Delicatessen (1991–2023)
• La Carreta Mexican Restaurant (1990–2020s)
• La Moule
• Lazy Susan (2020–2023)
• Le Bistro Montage
• Lincoln Restaurant (2008–2017)
• The Liquor Store (2015–2020)
• Little Bird Bistro (2010–2019)
• Local Lounge (2010–2021)
• Lonesome's Pizza (2010–2017)
• Lovely Hula Hands (2003–2009)
• Lucier (2008)
• Malka (2020–2023)
• Mama Đút (2020–2023)
• Masia
• The Matador (1971–2014)
• Metrovino
• Mi Mero Mole (2011–2020)
• Ned Ludd
• Nel Centro (2009–2020)
• New Copper Penny
• No Vacancy Lounge
• NOLA Doughnuts
• Ocean City Seafood Restaurant (2009–2020s)
• Olympia Provisions Public House
• Organ Grinder Restaurant
• Original Taco House (1960–2017)
• Overlook Restaurant (1974–2018)
• The Pagoda (1940–2008)
• Paley's Place (1995–2021)
• Paragon
• The Parish (2012–2016)
• Pazzo Ristorante
• PDX671
• Pearl Tavern (2016–2018)
• Phở Gabo
• Pied Cow Coffeehouse
• Ping (2009–2012; 2020–2021)
• Pink Feather (1957–2017)
• Pok Pok (2005–2020)
• Portland Penny Diner (2012–2017)
• Portobello Vegan Trattoria (2008–2016)
• Purrington's Cat Lounge
• The Queen's Head (2021–2022)
• Radar (2012–2022)
• Raven & Rose
• Red and Black Cafe (2000–2015)
• Revelry (2016–2020)
• RingSide Fish House (2011–2018)
• Ripe Cooperative
• Roman Candle (2013–2018)
• Roost
• The Roxy (1994–2022)
• Santa Fe Taqueria (1990–2024)
• Satyricon
• Saucebox (1995–2020)
• Seastar Bakery
• Shift Drinks (2015–2020)
• Shine Distillery and Grill (2019–2023)
• Shizuku by Chef Naoko
• Shut Up and Eat
• Sissy Bar (2022–2024)
• Southeast Grind (2009–2019)
• Stacked Sandwich Shop (2017–2021; 2023)
• Stanich's
• Starky's (1984–2015)
• The Sudra
• Sunshine Noodles (2019–2022)
• Sunshine Tavern (2011–2017)
• SuperBite
• Sweet Hereafter (2011–2024)
• Sweet Lorraine's (2021–2024)
• Tails & Trotters
• Tanuki
• Tapalaya (2008–2019)
• Tasty n Alder (2013–2020)
• Tasty n Daughters (2019–2020)
• Tasty n Sons (–2019)
• Tercet
• There Be Monsters
• Three Sisters Tavern (1964–2004)
• Tilt (2012)
• Toki
• Toro Bravo (2007–2020)
• Touché Restaurant & Bar (1995–2017)
• Vault Cocktail Lounge
• Veritable Quandary (1971–2016)
• Via Tribunali
• Victory Bar (c. 2006–2019)
• Whiskey Soda Lounge
• Wildwood (1994–2014)
• Wong's King (2004–2020)
• The Woodsman Tavern (2011–2018; 2021–2023)
• Xico (2012–2023)
• Yaw's Top Notch
• Yonder (2019–2022)
• Zefiro (1990–2000)

• Boxer Ramen

Notable defunct food cart pods include:

• Alder Street food cart pod (1990s–2019)
• Carts on Foster

• List of defunct restaurants of the United States