The following is a list of characters that first appeared on the Channel 4 soap opera Hollyoaks in 2000, by first appearance.

Matthew "Matt" Musgrove is a fictional character from the long-running Channel 4 soap opera Brookside, and later Hollyoaks, played by Kristian Ealey. After his initial appearance in Brookside, the character transferred as a regular on its sister show Hollyoaks. Kristian Ealey died on 3 May 2016, aged 38.^[1]

Matt first appears on Brookside Close when he and his family move into Number 8 in October 1998. During his time on the close, Matt befriends Tim O'Leary, Leo Johnson and his cousin Jerome. Matt becomes involved in marijuana, and various fights. Matt's older brother, Luke is accused of raping neighbour Nikki Shadwick, which leads to a feud between the Musgrove and Shadwick families. In early 2000, The Musgroves leave Brookside Close due to Luke's confession to raping Nikki.

In February 2000, Matt moves to Hollyoaks village in Chester as a janitor at Hollyoaks Community College, where he becomes close friends with Theo Sankofa and Alex Bell. He then falls for student and radio show host Chloe Bruce. However, he is not keen on asking Chloe out as he feels that she may dislike him due to his occupation. Therefore, Matt decides to phone her on her radio show and pretend to be someone else. When Matt finally reveals himself, Chloe is disappointed – leaving Matt's worst fears confirmed.

Despite this setback, Chloe decides to give Matt a chance and the pair become a couple. The relationship is going well, until Chloe has self-image issues and begins to push Matt away. This results in the pair breaking up, which leaves Matt disappointed due to his love for her. Matt ends up having a one-night stand with new student Eve Crawford, but he is reluctant not to carry on with the relationship, as it is Chloe who he wants to be with. Eventually, Matt and Chloe get back together, as Matt supports her through her problems. Matt eventually proposes to Chloe. The pair become engaged and Chloe's demands for the wedding prove to be expensive. However, Matt is adamant to give her the best wedding ever. He turns to The Loft owner Scott Anderson, and soon becomes involved in Scott's counterfeit money scam. Matt manages to pay for the wedding with counterfeit money, but it proves costly. On his wedding day, the police turn up and Chloe learns the truth about Matt's dealings with Scott. Knowing about Matt lies, Chloe decides she does not want to go through with the wedding, leaving Matt to face the police on his own. Matt makes a brief return in August 2004 in order to win Chloe back. Chloe considers at it at first but ultimately she refuses and leaves Matt on the platform as she boards the train to London.

Matt makes a brief return in 2004, in the late night spin-off Hollyoaks: After Hours, where he is working as a sailor and helps Ben Davies, Jake Dean, Joe Spencer and Dan Hunter escape from a mob who are running after them.

Kenneth “Kenny” Boyd, played by Greg Wood was a friend of Mark Gibbs (Colin Parry). Wood notably returned to Hollyoaks in 2013 playing a different character, Trevor Royle.

Kenny helped Mark with his feud with Luke Morgan (Gary Lucy) in which they attacked Luke. When Luke tried to break Mark's leg, a car chase ensued where Mark, Kenny and their friend caught up to Luke. They attacked him and pinned him down to his car, but Mark raped Luke and Kenny backed off, horrified. Kenny later was found guilty of rape along with Mark however the judge ruled Kenny to be heavily influenced by Mark's dominated nature and sentenced Kenny to three year imprisonment.

Lorraine Wilson is a fictional character on the long-running Channel 4 British television soap opera Hollyoaks. She appears throughout 2000 and is played by Jo-Anne Knowles. Lorraine is a night club owner. She meets and befriends Lewis Richardson (Ben Hull). Lewis begins gambling in a casino she owns and after he mounts up a debt she loans him money. She offers Lewis the option to cancel the debt by having sex with her which Lewis agrees to. Lorraine has been described as a "randy older woman" while her storyline with Lewis was described as a "sizzling sex shocker".^[2]

Taylor James, played by Michael Prince, made his first appearance on 17 April 2000. Taylor was a student at Hollyoaks Community College. He worked on the school radio station with Alex Bell, as well as a journalist for The Review. In October 2000, Taylor witnessed a drug deal by Lorraine Wilson's guards at The Loft, and informed Lewis Richardson. Lewis refused to do anything about the situation, resulting in a loud confrontation between the pair. Upon leaving the club, Taylor was followed by the guards and viciously assaulted.

Jess Holt, played by Frankie Hough, first appeared in 2000 before leaving in 2001. Jess was a prostitute and girlfriend of Sol Patrick (Paul Danan), who she met whilst he was homeless, when he helped her escape from her pimp Steve. When Sol moved back to The Dog in the Pond, he brought Jess with him. However Steve found her and torched the pub on New Year's Eve 2000, leaving Jess almost blind. Jess remained living with Sol and was given a job at Deva by Andy (Ross Davidson) and Sue Morgan (Eve White). Steve refused to back down and confronted both Jess and Sol, which escalated when Steve fell off a barge and was knocked unconscious. When Steve recovered from his injuries, he returned for a final showdown which led to Jess pushing him over The Loft balcony. Jess and Sol decided to flee the village to avoid imprisonment over Steve's attack.

Frankie Hough died on 13 May 2023, aged 38, while 18 weeks pregnant after being involved in a car accident with her 9-year-old son and 4-year-old nephew.^[3]

Detective Inspector William "Will" Davies was played by Barny Clevely between 2000 and 2004, with a brief return from 8–11 April 2005.

Will is portrayed as laid back but responsible and supportive to his children Ben and Abby. Will began early on dating Sue Morgan and the relationship seemed to be going reasonably well until Sue decided to return to her husband Andy. Will was devastated as he was deeply in love with her, and on several occasions he tried to persuaded Sue away from Andy, but it did not change her mind. With the help of Ben, Will decided to move on. In Hollyoaks, murders began happening with the targets being young blonde girls and Will was under pressure by the residents of the village after he failed to discover any further leads. In came DCI Dale Jackson, who took over the case and Will got major designs on his colleague, when he asked her to move in with the Davies. Abby was certainly pleased and hoped that Will could find happiness with Dale, but Ben disliked the idea.

One night, Will was left shocked and devastated when he caught Dale and Ben in bed together. An ashamed Ben tried to apologise; however, Will insisted that it really never bothered him and made it clear to Ben that he was free to do anything he wanted. However, another twist emerged when Dale told Will she had feelings for him and the pair began to date, despite Ben’s warnings. Ben was furious at his father's actions and accused Dale of using him, leading Will to throw Ben out of his own house. Eventually, Will and Ben made up, but Will was to face another shock when Dale left after being sacked by the commissioner. Another setback then followed for Will when Ben got Will's assistant officer, Emma chambers, pregnant. What Ben was unaware of was that Emma had had an affair with Will several years ago when he was married to Ben's mum, which had caused the splitting of his parents. Ben was angry with Will for not telling him, but both father and son made their amends. Will supported his son Ben through his failed marriage with Izzy Cornwell and also supported his daughter Abby through her troubles. Will went on to receive a job offer in London and moved away from Hollyoaks.

In April 2005, Will returned for a visit when Ben's friend Lisa Hunter told him Ben had re-injured his broken leg and had been put back in hospital. During his brief stay, Steph Dean tried to fix him up with her mother, Frankie Osborne. Will thought they were only going to have a friendly dinner with her and her husband Johnno, as he had no idea that Johnno had left her. After dinner, Will said he wouldn't be back in town for some time, and as Frankie apologised, Steph and Craig threw him out under their misguided notion he was abandoning their family just as their father had. The next day, Ben was released from hospital, and told his father to return to London so he wouldn't lose any pay.