Lignum is Latin for wood and may refer to:

• Gmelina lignum-vitreum, plant endemic to New Caledonia
• Lignum, common name of Muehlenbeckia florulenta, plant native to inland Australia
• Lignum Crucis, remnants of the True Cross
• Lignum Ltd, see John C. Kerr
• Lignum vitae, trade wood from trees of the genus Guaiacum
• Lignumvitae Key, island in the Florida Keys
• Vitex lignum-vitae, Australian rainforest tree
• Lignum, Virginia, unincorporated community in the United States

• Lignin

This disambiguation page lists articles associated with the title Lignum.
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